Latest Research Preprints - Life Science Network

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This list contains preprints from the last 30 days only. Use the search function to access older preprints.

The default sorting of preprints in this list is by the date when the preprint was uploaded or imported to our database (shown on top). Publication date is indicated below the title.

Created 16 Oct 2026

The Signaling Pathway of a Bacterial Two-Component System Determined by cryo-EM

by Karki, P., Hernandez, C., Mendez, J. H., Budell, W. C., Menendez, D., Kanou, S., Abuhashish, R., Bizhga, D., Malla, T. N., Schwander, P., Stojkovic, E. A., Schmidt, M.
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Created 16 Oct 2026

SMARTFlexDB: a paired apo-holo RNA structure database and analysis platform for RNA conformational flexibility and small-molecule recognition

by Jiang, S., Wei, J., Taghavi, A., Seabra, G., Childs-Disney, J. L., Li, C., Disney, M. D., Li, Y.
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Created 16 Oct 2026

Pre-binning correction of chimeric contigs reduces reference-discordant gene annotations in near-complete metagenome-assembled genomes

by Ding, Y., Xiao, J., Zou, B., Yang, C., Wu, Z., Lyu, A., Zhang, L.
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Created 16 Oct 2026

DIPLER: rapid k-mer-based locus identification

by Kivirüüt, K. R., Kaplinski, L., Salumets, A., Puurand, T.
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Created 16 Oct 2026

Allosteric covalent inhibition of cereblon through cryptic cysteine targeting

by Rizvi, Z., Nordin, B. E., Symons, K. T., Baltgalvis, K. A., Weinstein, D. S., Patricelli, M. P., Simon, G., Lander, G. C.
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Created 16 Oct 2026

P4HA1 and P4HA2 accept both shared and isoenzyme-specific substrate residues in type I collagen to directly and indirectly orchestrate its post-translational modification landscape

by Helle, D., Robert, A., Ramalanjaona, N., Bui, C., Gulberti, S., VINCOURT, J.-B.
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Created 16 Oct 2026

A Benchmark of Unsupervised Circadian Phase Inference Methods for Bulk Transcriptomic Data

by Purohit, S., Grant, G. R., Brooks, T. G.
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Created 16 Oct 2026

NoiTox: A Machine Learning Strategy for Peptide Toxicity Prediction Reveals Label Noise in Benchmark Datasets

by Almeida, G. O., Albuquerque, M. C., Silva, B. M., Silva, O. A. B., Ferreira, R. S., Meira, W., Pires, D. V., Prata, W. M., Silveira, S. A.
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Created 16 Oct 2026

Benchmarking the Performance of a Commercial Electrostatic Linear Ion Trap (ELIT) Charge Detection Mass Spectrometer For Higher-Order Antibody Aggregate Analysis

by Wu, S.-Y., Guo, X.-M., Lv, J.-Y., Li, Y.-Z., Gu, L., Tian, Z., Xiao, Y.-S., Christofi, E., Haris, A., Lu, H., Wang, R., Xie, H.-F., Li, H., Pan, Y., Zhou, M., Fang, W.-J.
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Created 16 Oct 2026

Rationally Engineered Self-Assembling Protein Nanoparticles for Allergen-Specific Peanut Allergy Immunotherapy

by Zhang, Y.-N., DesRoberts, C., He, L., Zhu, J.
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