Preprints

Created 16 Oct 2026

Dual-graph deconvolution of enzyme fitness: an interpretable framework to identify and explain catalytic modulators

by Garcia Busto, S., Eschbach, E., Hopf, T. A., Sander, C., Bacallado, S., Marks, D. S.

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Created 16 Oct 2026

Systematic evaluation of transcript normalization methods and quantification pipelines across long-read sequencing platforms

by Paniagua, A., Jetzinger, F., Tarazona, S., Conesa, A.

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Created 16 Oct 2026

Programmable design of functional RNAs through multimodal generative learning

by Ma, J., Zhu, J., Huang, W., Mu, K., Huang, K., Dong, Z., Guo, F., Xie, X., Shao, Y., Huber, R., Wan, Y., Zhang, L., Wu, Q., Zhang, Q. C.

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Created 16 Oct 2026

Longitudinal treatment selection under irreversible discontinuation: History-aware prediction and trajectory-aware learning in peanut-allergy prevention

by Taub, R., Wasserman, T., Savir, Y.

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Created 16 Oct 2026

Global signatures of Ribonucleotide Excision Repair deficiency and its therapeutic vulnerabilities

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Created 16 Oct 2026

Bidirectional changes in seabird populations drive terrestrial ecosystem function and biodiversity

by Guy, M., Johnson, D., Caruso, T., Park, K., Gilbert, L.

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Created 16 Oct 2026

High-throughput genetic interaction analysis in Mycobacterium tuberculosis identifies highly synergistic drug targets

by Chapman, C. L., Wang, X., Adolph, C. R., Fineran, P. C., Cook, G., Jackson, S. A., McNeil, M.

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Created 16 Oct 2026

High variability and limited host specificity characterise the microbiome of Desmophyllum pertusum across a cold-water coral reef

by Stevenne, C., Pruckner, C., Larsson, A. I., Strömberg, S. M., Espinel-Velasco, N., D'Hondt, S., Haring, E., Kapun, M., Frade, P. R.

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Created 16 Oct 2026

A molecular clutch governs stator engagement and flagellar torque

by Guo, W., Yue, J., Zhang, K., Mao, E., Wang, J., Guo, J., Yu, H., MOTALEB, M. A., Li, C. A., Liu, J.

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Created 16 Oct 2026

Polysaccharide release factors drive lipid-carrier recycling in bacteria

by Voedts, H., Verstraete, O., Auger, R., Patin, D., Jacobs, J., Bommer, G. T., Arthur, M., HUGONNET, J.-E., Iorga, B. I., Touze, T., Collet, J.-F.

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