Preprints

Created 30 Sep 2026

Analysis of SpCas9 on- and off-target effects in high efficiency multiplex editing in Arabidopsis

by Stuttmann, J., Keilwagen, J., Ortet, P., Lim, F.-S., Schmutzer, T., Llauro, C., Mbodj, A., Mirouze, M., Hartung, F., Wilhelm, R.

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Created 30 Sep 2026

PfPHAST: Plasmodium falciparum Public Health Amplicon Sequencing Tool, a Streamlined Panel for Malaria Genomic Surveillance

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Created 30 Sep 2026

Combined negative effects of simultaneous perturbations on grassland functionality

by Fioratti, M., Gombeer, S., Holmes, J., Zimmerman, S., Rillig, M. C., Risch, A. C., Cordero, I.

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Created 30 Sep 2026

Unraveling the metabolic landscape of alkaptonuria through a human-relevant in vitro liver disease model

by Rombaut, M., Del'haye, G., Lequeue, S., Norman, B. P., Desmet, L., Salvi, N., Heymans, A., Neuckermans, J., Hughes, J. H., Ates, G., Massie, A., Vanhaecke, T., Bou-Gharios, G., De Kock, J.

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Created 30 Sep 2026

Dietary selenium deficiency drives sex-specific circadian disturbance through redox imbalance and causes early systolic dysfunction in mice

by Guo, X., Lambregtse, F., Geerlings, L., Zhu, J., Zijlstra, S. N., Feringa, A. M., Schouten, E. M., Sillje, H. H., Schomburg, L., van der Meer, P., Bomer, N.

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Created 30 Sep 2026

Dysregulation of FMR1 Splicing in Human Fragile X Syndrome

by Jung, S., Richter, J. D.

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Created 30 Sep 2026

Isogenic forebrain organoids uncover early neurodevelopmental alterations and imbalances in neuronal function leading to hyperexcitation in Gaucher disease

by Crowe, J. A., Matusova, Z., Girard, A. S., Rajon, A., Colameo, D., Oburoglu, L., Zetterdahl, O. G., Bjorklund, J., Puigsasllosas Pastor, C., Krupp, S., Ellervik, U., Cremonesi, A., Tornero, D., Penton Ribas, D., Ahlenius, H., Valihrach, L., Canals, I.

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Created 30 Sep 2026

Oxytocin and Vasopressin Immunoreactivity Differs Across Auditory Brainstem Nuclei in Rodents with Distinct Social Systems

by Joseph, L., Boren, L., Ingram, G. E., McCullagh, E. A.

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Created 30 Sep 2026

Macrophage-derived IL-27 sustains autoreactive CD8+ cytotoxic T cells in autoimmune hepatitis

by Hao, K., Baptista, S. G., Beaumond, A. S. V., Schafer, D. M., Kaja, P. L., Chiang, K., Gao, K. M., Nundel, K., Kumar, S. V., Sherman, M. S., Marshak-Rothstein, A., Varanasi, S. K.

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Created 30 Sep 2026

Identification of Novel Inhibitors of JEV RdRp as Potent Antiviral Drugs: Targeting NS5-NS3 Protein Interaction

by Mishra, P., Mishra, S., Srivastava, G., Archana, K., Siddiqi, M. I., Haldar, S., Tripathi, R. K.

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