Latest Research Preprints - Life Science Network

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This list contains preprints from the last 30 days only. Use the search function to access older preprints.

The default sorting of preprints in this list is by the date when the preprint was uploaded or imported to our database (shown on top). Publication date is indicated below the title.

Created 29 Sep 2026

A Minimally Perturbative DARPin Probe for Quantitative Fluorescence Imaging of the Human TCR-CD3 Complex

by Pons Romero, M., Kalouskova, B., Kloimwieder, J., Linares, A., Majkova, A., Riedl, L., Kopittke, C., Bishara, M., Brameshuber, M., Sevcsik, E.
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Created 29 Sep 2026

Combining CHARMM36m with OPC water improves accuracy

by Kozlowski, N., Nagy, G., Ottoway, C. F., Bock, L. V., Vaiana, S. M., Grubmuller, H.
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Created 29 Sep 2026

Targeted finetuning enables co-folding models to learn ligand-induced protein conformational states

by Gorantla, R., Schleberger, C., Sesterhenn, F.
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Created 29 Sep 2026

CryoMV: Structure-Prior-Guided Modeling and Real-Particle Validation of Continuous Conformational Transitions in Cryo-EM

by Li, F., Dong, H., Tang, S., Wang, X., Zhang, C., Ji, C., Han, R., Zhang, F., Wan, X.
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Created 29 Sep 2026

Benchmarking single-cell foundation models for aging biology

by Ni, X., Liang, Y., Zhu, J., Zhang, L., Shen, X., Yang, M., Xu, R., Li, H., Ji, R., Jin, C., Ni, S.
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Created 29 Sep 2026

UniWave-2: A Hybrid Model for Nucleic Acid Waveform Feature Extraction Enhanced by Fourier and Wavelet Transforms

by Zhang, H., Qi, Y., Feng, Y., Wang, L.
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Created 29 Sep 2026

DSSNA: An Open-Source GROMACS Module for Automated Analysis of Nucleic Acid Secondary and Tertiary Structure in Molecular Dynamics Simulations

by Gorelov, S., Konevega, A., Shvetsov, A.
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Created 29 Sep 2026

CheckAMG: Accurate Identification of Auxiliary Viral Genes with Genome-Language Models

by Kosmopoulos, J. C., Martin, C., Wainaina, J. M., Bolduc, B., Urvoy, M., Sullivan, M. B., Anantharaman, K.
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Created 29 Sep 2026

Common viral infections seed regionally distinct resident memory T cells in the human CNS

by Degefu, H. N., Searles, T. G., Chen, T., Musial, S. C., Isaacs, J. F., Kleist, S. A., Yang, S., Ford, M. A., Kolling, F. W., Turk, M. J., Skorput, A. G. J., Lin, C.-C., Zanazzi, G. J., Hong, J., Song, L., Rosato, P. C.
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Created 29 Sep 2026

Neurodegeneration-inducing macromolecules exit the brain via nanovascular conduits formed by reticular fibroblasts

by Nortley, R., Anderle, S., Sideris-Lampretsas, G., Davis, H., Sethi, H., Alasaadi, D., Acton, S. E., Attwell, D.
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