Latest Research Preprints - Life Science Network

Preprints

The Preprints module of the Life Science Network is an archive of pre-publication manuscripts. You can use it to upload your own preprints and give your research more exposure. Preprints may also be automatically imported from other databases.

You can upload a preprint here

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This list contains preprints from the last 30 days only. Use the search function to access older preprints.

The default sorting of preprints in this list is by the date when the preprint was uploaded or imported to our database (shown on top). Publication date is indicated below the title.

Created 19 Oct 2026

DeepD enables efficient genome modeling and controllable long-context sequence generation across domains of life

by Lai, J., Xin, B., Wang, Z., Yu, A., Chen, Z., Guo, Y., Zhang, M., Hu, B., Ye, C., Chen, J., Liu, Q., Zhao, H., Song, W., Dong, N., Yang, F., Yang, Q., Zhao, H.
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Created 19 Oct 2026

DIMPLE: A Tree-Guided Divide-and-Conquer Framework for ILS-Aware Phylogenetic Network Inference on Large-Scale Data

by Guang, Z., Sapoval, N., Yan, Z., Kessler, M., Nakhleh, L.
- Views 12
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Created 19 Oct 2026

Relation-Aware Graph-Hypergraph Networks for Antibody Sequence-Structure Co-Design

by Wei, J., Zhang, S., Duan, H., Wei, L., GUO, J.
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Created 19 Oct 2026

Determinants of cysteine coverage by chemoproteomics
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Created 19 Oct 2026

FluOpti: an open-source system for programmable whole-plate optogenetics and multi-fluorescence imaging

by Nunez, I., Matute, T., Aravena, A., Araya, W., Nunez, D., Cazaux, S., Ferrando, V., Obregon, P., Quero, F. J., Düring, G., Rudge, T., Federici, F.
- Views 9
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Created 19 Oct 2026

Comparison of the performance of sporophytes derived from narrow and wide genetic crosses between strains of the cultivated kelp Saccharina latissima
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Created 19 Oct 2026

Dietary phosphorus restriction enables multigenerational breeding of α-Klotho-deficient rats

by Sarai, C., Totsuka, Y., Horii, T., Tamura, S., Gouda, E., Kojima, S., Kouki, T., Ohno, N., Yoshiki, A., Ohmori, T., Kurosu, H., Endo, H., Tominaga, K., Hatada, I., Yamamoto, T., Kuro-o, M., Nagao, Y.
- Views 10
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Created 19 Oct 2026

CAPO: Compute-Aware Automated Protein-Model Optimization

by Schifferli, T., Garcia Pardinas, J., B. Irvine, E., Hartley, M.-A., Bikias, T.
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Created 19 Oct 2026

Beyond Better Models: Barriers and a Path Forward in Generalisable TCR Antigen Specificity Prediction

by Koohy, H., Ilievski, I., Antanaviciute, A., Ogg, G.
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Created 19 Oct 2026

A Humanized Mouse Model of DRPLA Recapitulates Epilepsy and Demonstrates Antisense Oligonucleotide-Mediated Disease Modification

by WU, Q., Erickson, I., Davidson, S., Shonka, S., Smith, V., Gidi, B., Knox, K., Yu, T. W., Khurana, V., Carroll, J., Korecka, J. A., Barker-Haliski, M.
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