Latest Research Preprints - Life Science Network

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This list contains preprints from the last 30 days only. Use the search function to access older preprints.

The default sorting of preprints in this list is by the date when the preprint was uploaded or imported to our database (shown on top). Publication date is indicated below the title.

Created 23 Sep 2026

Starship transposons mobilise via a circular intermediate with potential biotechnological applications

by Baericke, A., Jameson, V., Urquhart, A. S.
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Created 23 Sep 2026

Caloric restriction drives age-dependent and integrated remodeling of RNA processing and lipid composition in mouse brain

by Tye, S. A., Clark, J. P., Engeler, A. J., Singh, A., Anderson, R. M., Rhoads, T. W.
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Created 23 Sep 2026

A fibroblast-rich transcriptomic axis reflects stromal remodeling within the CMS4 phenotype in colorectal cancer

by Zheng, Y., Hao, S., Jiang, C.
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Created 23 Sep 2026

Zika virus oncolytic signaling reverts immunosuppressive and angiogenic glioblastoma microenvironment in vitro and in vivo
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Created 23 Sep 2026

Nanobody-Functionalized AAV achieves Promoter-independent Neuronal Targeting in the CNS

by Extross, A., Fernandez de Velasco, E. M., He, Y., Wickman, K., Schmidt, D.
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Created 23 Sep 2026

MCT1 activity defines an aggressive metabolic phenotype and therapeutic target in non-small cell lung cancer

by Cameron, R. B., Shema, K. E., Dubois, N., Clare, M. G., Hammond, N. G., Kaur, M., Chang, B. K., Schechter, E. G., Hsiang, J., Marczenia, Z., Garassino, M. C., Cai, L., Bestvina, C. M., Mathews, T. P., Tasdogan, A., Shah, H., Faubert, B.
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Created 23 Sep 2026

A step toward synthetic endosymbiosis: introducing Escherichia coli and the trypanosomatid endosymbiont Candidatus Kinetoplastibacterium crithidii into mammalian cells using a polyethylene glycol-based fusion protocol

by Pednekar, R., van Geelen-Kuenzel, N., Diehl, C. M., Koch, L.-A., Llorente, B., Nowack, E. C. M., Zurbriggen, M. D.
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Created 23 Sep 2026

SWELL1 channel-mediated D-2HG export promotes immune evasion and metabolic fitness in IDH-mutant gliomas

by Cheng, H. Y., Ma, L., Chen, J., Huang, J., Chen, L., Liu, W., Liu, Y., Zhao, R., Ye, Y., Zheng, W., Kratz, L., Castro, M., Sun, S., Zhu, J., Han, L., Qiu, Z.
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Created 23 Sep 2026

Targeting the CDK4-Cyclin D Complex: A New Generation of Selective Kinase Inhibitors for Cancer Therapy

by Fuentes-Baile, M., Encinar, J. A., Araujo-Abad, S., Perez-Valenciano, E., Garcia-Morales, P., Fuertes-Garcia, L., de Juan Romero, C., Saceda, M.
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Created 23 Sep 2026

A tumor-cell MHC-II program is associated with checkpoint-blockade outcomes across stages of bladder cancer
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