Latest Research Preprints - Life Science Network

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This list contains preprints from the last 30 days only. Use the search function to access older preprints.

The default sorting of preprints in this list is by the date when the preprint was uploaded or imported to our database (shown on top). Publication date is indicated below the title.

Created 24 Aug 2026

CRISPR/Cas9-Mediated Knockout of ZFP36L1 Impairs Cell Proliferation, Alters Cell-Cycle Progression, and Enhances DNA Damage Responses in MDA-MB-231 Triple-Negative Breast Cancer Cells

by Gandu, H. H. G., Gandu, P. T. Y., Okorare, E., Ochem, M. U., Okeke, N. H., Nwachi, D. O., Yusuf, D. K., Anene, N. G., Hamed, R. G. A., Shuaib, U. K.
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Created 24 Aug 2026

Distributions of threshold crossing times of messenger RNA

by Verma, A. K., Barman, H. K., Rijal, K., Das, D.
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Created 24 Aug 2026

Implicit Hierarchical Tensor Decomposition of Single-Cell Four-Omics Data Reveals Cell-Type-Associated Enhancer--Promoter Regulatory Programs

by Taguchi, Y.-h., Turki, T.
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Created 24 Aug 2026

sc-pcQTL: hurdle-based co-expression modeling for multi-gene QTL mapping in single-cell RNA-seq data

by Zhang, J., Huang, Y., Claussnitzer, M., Kanai, M., Zhou, W.
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Created 24 Aug 2026

Mountain Centroid: RNA Ensemble Representation with Mountain Profiles

by Otagaki, T., Asai, K., Sato, K.
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Created 24 Aug 2026

Classifying CRISPR-Cas9 Off-Target Cleavage Sites from GUIDE-seq Data: A Class-Imbalanced Machine Learning Benchmark

by Sarvi, D., Alasyam, J.
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Created 24 Aug 2026

Potential impacts of supplementing next generation long-lasting insecticidal nets with household-scale micro-mosaic deployment of indoor residual spraying with insecticides upon rates of incipient resistance trait emergence and selection

by Chinula, D., Mziray, N., Hobbs, N. P., Hamainza, B., Reed, T., Kiware, S., Killeen, G. F.
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Created 24 Aug 2026

Trehalose exerts cryoprotective effects on piglet testicular tissue

by Huang, Y., Liu, N., Liu, J., Wei, Y., Wang, X., Li, X., Xu, C., Zheng, J., Hu, C.
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Created 24 Aug 2026

IL-10/ACOD1 axis regulates catabolism of phagocytosed lipids in trained macrophages

by Reynolds, M. B., Bond, A., Fennell, E. M. J., Grae, K. J., Joulia, E., Donnelly, M. P., Johnson, M. A., Laguerre, A., Rojas, G. R., Kolar, M. J., Ayres, J. S., Metallo, C. M., Shadel, G. S.
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Created 24 Aug 2026

A Shifting Immune Landscape: ILC Redistribution and Neutrophil Polarization in Vascular Cognitive Impairment and Dementia (VCID)

by Wang, L. P., Naeini, S. E., Bhandari, B., Rush, L., Rogers, H. M., Khodadadi, H., Wakade, C., Yu, J. C., Hess, D. C., Lopes Salles, E., Baban, B.
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