Preprints

Created 16 Aug 2026

Directing the Chondro-Fibro Axis via Early Microenvironmental Interactions to Enable Precise and Volumetric Cartilage Repair

by Hasson, M., Solomon, H., Chihab, S., Hartzler, A., Fernandes, L. M., Zhao, A., Patton, W. X., Morgan, N., Liu, A. Y., Khan, N. M., Kaiser, J. M., Patel, J. M.

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Created 16 Aug 2026

Structural basis of K<+>/H<+> antiport in YcgO and its inhibition by unphosphorylated PtsN

by Srivastava, A., Athreya, A., Patidar, Y., Singh, V., Sardesai, A. A., Penmatsa, A.

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Created 16 Aug 2026

Activity-based chemical proteomics uncovers unexpected covalent targetsof E64d and reveals a role for cysteine cathepsins in PLD3 proteostasis.

by Hertwig, M., Kielkowski, P.

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Created 16 Aug 2026

Molecular orchestration of global actin remodelling by INF2

by Uecker, F., Wargenau, S., Boiero Sanders, M., Prange, L., Jekabson, R., Janning, A., Krausel, V., Gass, M., Pavenstaedt, H., Braun, D., Krahn, M. P., Schuberth, C., Raunser, S., Bieling, P., Wedlich-Soldner, R.

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Created 16 Aug 2026

Trustworthy in silico labeling via semantic visual interpretability of image-to-image translation

by Ben Nedava, L., Miller, G., Elmalam, N., Viana, M. P., Chen, J., Gaudreault, N., Rafelski, S. M., Zaritsky, A.

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Created 16 Aug 2026

Single-Cell Mapping of tRNA Expression Dynamics Across Human Hematopoiesis

by Külp, M., Osuna Lopez, M., Wiegand, A.-S., Perner, S. P., Cetin, R., Matthess, Y., Günther, S., Schmachtel, T., Schultheis, H., Looso, M., Kaulich, M., Häupl, B., Oellerich, T., Benes, V., Bonig, H., Rieger, M. A.

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Created 16 Aug 2026

Healing of chromosomal breaks is impeded in cells expressing progerin

by Bondurant, A. A., Grove, E. K., Van, N. M., DiCintio, A. J., Waldman, A. S.

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Created 16 Aug 2026

Diurnal time and sleep pressure modulate cerebrospinal fluid low-frequency oscillations in synchrony with wake-promoting nuclei

by Brendstrup-Brix, K., Iversen, O. B., Ferdinando, H., Moradi, S., Bergmann, M. L., Pernet, C., Myllyla, T., Ulv Larsen, S. M., Knudsen, G. M.

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Created 16 Aug 2026

Potential benefit of loss-of-function on bacterial fitness

by Hidalgo, D., Soto-Avila, L., Aguilar-Vera, O. A., Ledezma-Tejeida, D., Farias-Rico, J. A., Utrilla, J.

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Created 16 Aug 2026

PDE3A-SLFN12 Molecular Glues Target Multiple KIT D816V Cell Types in Preclinical Models of Mast Cell Malignancies

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