Latest Research Preprints - Life Science Network

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This list contains preprints from the last 30 days only. Use the search function to access older preprints.

The default sorting of preprints in this list is by the date when the preprint was uploaded or imported to our database (shown on top). Publication date is indicated below the title.

Created 10 Jul 2026

Liver microbiome composition associates with histological severity and PNPLA3 genotype in metabolic dysfunction-associated steatotic liver disease

by Mascardi, M. F., Taussig, R., Signoretta, I. P., Suarez, B., Marciano, S., Casciato, P., Narvaez, A., Haddad, L., Gadano, A., Penas-Steinhardt, A., Bustamante, J. P., Trinks, J.
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Created 10 Jul 2026

Shield-4i: A Whole-mount Multiplexed Imaging Platform for Studying Multiscale Information Flow in 3D Multicellular Systems

by Hornbachner, R., Shamipour, S., Arslan, F. N., Fan, R., Hess, M., Curvaia, F., Lüthi, J., Oates, A. C., Bedzhov, I., Gilmour, D., Uhlmann, V., Pelkmans, L.
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Created 10 Jul 2026

Linker-Length Landscape Mapping Enables Coupling of Diverse Synthetic Chemically Induced Dimerization Systems to Molecular Readouts

by Pan, Y., Kang, S., Nakajima An, D., Yu, Y., DiMaio, F., Gu, L.
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Created 10 Jul 2026

NNMT Loss Drives Cancer Progression by enhancing SAM availability for mTORC1 Signaling and Chromatin Methylation

by Deng, Q., Mitchell-Velasquez, E., Venkatesh, S., Mannan, R., Cho, H., Alhusayan, M., Yashfeen, A., Natesan, R., Bhanu, N. V., Paturu, R., Siddique, J., Mehra, R., Varambally, S., Garcia, B., Feldser, D., Lal, P., Chinnaiyan, A. M., Asangani, I. A.
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Created 10 Jul 2026

SMAD4 MH2 Mutations Disrupt CREBBP/EP300 Recruitment and TGF-β-Induced Transcription in Colorectal Cancer

by Islam, M. S., Nizamuddin, S., Haw Chan, T. E., Fotouhi, O., Koidl, S., Timmers, H. T. M.
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Created 10 Jul 2026

Smad1 and Smad5 differentially transduce BMP signaling during in vitro differentiation of mouse embryonic stem cells into dorsal interneurons

by Gallardo, S., Gupta, S., Verdin, Y., Rodriguez, C., Chilin, B., Derbarsegian, A., Gajardo Del Real, G., Butler, S. J.
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Created 10 Jul 2026

Rapid and efficient oligodendrocyte differentiation from human pluripotent stem cells via dual inhibition of BMP and Notch signaling

by Evangelisti, A., Phillips, S. M., Jungverdorben, J., Walsh, R. M., Wu, Y., Bocchi, V. D., Zhou, T., Studer, L.
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Created 10 Jul 2026

Trisomy 21 Impairs Development of Enteric Neural Crest-Derived Cells via SOD1-Mediated RET Dysregulation

by Singh, K., Liu, F., Zhao, A., Lohraseb, I., Davoli, T.
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Created 10 Jul 2026

Biological Network Organization, Not Generic Graph Topology, Drives Graph-Based Gene Essentiality Prediction

by Rahimi, S., Bonner, S., Afzal, A., Milo, M., Morrissey, E., Petsalaki, E.
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Created 10 Jul 2026

A Cross-Species Systems Genetics Framework Identifies Causal Genes in Diabetic Nephropathy

by Mishra, K., Sakban, R. B., Shankar, S., Wong, J., Farah, B. L., Guo, J., Ching, J., Tham, M. S., Kovalik, J.-P., Gurley, S. B., Petretto, E., Tolwinski, N. S., Coffman, T. M., Behmoaras, J.
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