Latest Research Preprints - Life Science Network

Preprints

The Preprints module of the Life Science Network is an archive of pre-publication manuscripts. You can use it to upload your own preprints and give your research more exposure. Preprints may also be automatically imported from other databases.

You can upload a preprint here

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This list contains preprints from the last 30 days only. Use the search function to access older preprints.

The default sorting of preprints in this list is by the date when the preprint was uploaded or imported to our database (shown on top). Publication date is indicated below the title.

Created 12 Oct 2026

Linker stretching optimizes bonding entropy in sticker-spacer condensates

by Akram, S. A., Liu, J., Chattaraj, A., Gautam, S., Chakrabarti, B., Shakhnovich, E., Schmit, J. D.
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Created 12 Oct 2026

Latent-Space Residue-Pair Networks from Molecular Dynamics Distinguish Ligand-Activated and SAVI-Associated STING

by Tsuchiya, Y., Yonezawa, Y.
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Created 12 Oct 2026

CRISCross: Integration of Epigenetic Information for Deep-Learning-Based Prediction of CRISPR-Cas9 Off-Targets Across Cell Types

by Jobson Pargeter, W., Rabsch, D., Kaufmann, M. M., Uhl, M., Mitrofanov, A., Brox, T., Cathomen, T., Tran, V. D., Backofen, R.
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Created 12 Oct 2026

DNA methylation-based prediction of differentiation state at cell-type resolution reveals an age-associated epigenetic mesenchymal drift

by Teschendorff, A., Tong, H., Guo, X.
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Created 12 Oct 2026

IsoGraph resolves coordinated transcript choice and gene abundance in the aging human brain

by Bennett, A., Johnson, E. K., Benjamin, K. J. M.
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Created 12 Oct 2026

Chain of Structures: Connecting Reasoning and Generation for Protein Design

by Cai, Q., Xu, M., Yan, J., Wang, Z., Liu, Y., Pei, Q., Zhang, Z.
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Created 12 Oct 2026

WarpDemuX-custom - Multiplexed sequence-specific direct RNA sequencing

by Naarmann-de Vries, I., van der Toorn, W., Mishra, S., Blank, M. F., Heid, D., Mueller-Tidow, C., von Kleist, M., Dieterich, C.
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Created 12 Oct 2026

PeTFlow: Flow-Matching Based All-Atom Peptide Design through Side-Chain State Tokenization

by Deng, Q., Xu, M., Chen, H., Lei, J.
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Created 12 Oct 2026

Large-scale pooled selection enables mapping of modifiers of RNAi gene knockdown effects in C. elegans

by Zdraljevic, S., Lee, A., Walter-McNeill, L., Marquez, H., Webster, A. K., Chitrakar, R., Blount, J., Baugh, L. R., Bloom, J. S., Kruglyak, L.
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Created 12 Oct 2026

Robust V(D)J Recombination in the Absence of SA1/2-mediated Chromatin Loops

by Yang, Z., Fu, Y., Mikhova, M., Chen, D., Hebert, C., Ye, A. Y., Lin, X., Williams, T., Hu, H., Ba, Z., Dekker, J., Alt, F. W.
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