Preprints

Created 20 Sep 2026

Cross-species spatial profiling links progranulin to an immune suppressive niche in brain metastasis

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Created 20 Sep 2026

Optimising MALDI on PEN substrates for small molecule analysis in the context of same-section multimodal workflows

by Delattre, H., Piper, S., Abdelhamed, A., von Gerichten, J., Bunch, J., Bailey, M., Steven, R. T.

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Created 20 Sep 2026

Analyzing globin gene variation in gnomAD: implications for variant interpretation in hemoglobinopathies

by Kontopoulou, M., Xenophontos, M., Lederer, C. W., Stephanou, C., Kountouris, P.

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Created 20 Sep 2026

A reference genome without a virus: cDNA reconstruction reveals the provenance and function of the MS2 phage sequence

by Small, E., Lasley, G., Layton, E., Wiwi, A., Del Curto, D., Weinstock, L. D., Thongchol, J., Zhang, J., CAHILL, J.

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Created 20 Sep 2026

CFTR dysfunction in the intestinal epithelium is sufficient to promote pathogenic expansion of E. coli and enhanced barrier permeability in cystic fibrosis

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Created 20 Sep 2026

An RNase Toxin Hijacks Elongation Factor-Tu to Cleave the Ribosomal Sarcin-Ricin Loop

by Hespanhol, J. T., Blackburn, T. M., Pham, K., Varshney, A., Nicastro, G. G., de Souza, R. F., Aravind, L., Johnson, A., Keiler, K. C., Dunham, C. M., Bayer-Santos, E.

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Created 20 Sep 2026

METTL3 promotes human coronavirus replication through an interferon-independent mechanism

by Dinesh, I., Fonseca, J. M. G. D., Ohnezeit, D., Elliott, G., Wilson, A. C., Burgess, H. M.

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Created 20 Sep 2026

A cis-encoded RNA interaction controls sub-operonic spoVG expression in Staphylococcus aureus

by Lynch, R., Pettersson, M., Coulon, P. M. L., Biazik, J. M., Tree, J. J., Mediati, D. G.

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Created 20 Sep 2026

Discovery and Structure Activity Relationship Optimization of a Novel Rv1625c Agonist Chemotype with Antitubercular Activity

by Xie, H., Sukheja, P., Tolentino, K., Webb, J., Woods, A., Chi, V., Kathayat, D., Montague, C. R., VanderVen, B. C., Winneroski, L., Durst, G., Mendel, D., Hipskind, P., Henry, K., McNamara, C. W., Yang, B., Chatterjee, A. K.

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Created 20 Sep 2026

A symbiont-derived biosurfactant couples bacterial surface behavior and host peristalsis to control colonization

by Pees, B., Escudero-Hernandez, C., von Hoyningen-Huene, A., Rosenstiel, P., Schmitz, R. A., Dierking, K.

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