Latest Research Preprints - Life Science Network

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This list contains preprints from the last 30 days only. Use the search function to access older preprints.

The default sorting of preprints in this list is by the date when the preprint was uploaded or imported to our database (shown on top). Publication date is indicated below the title.

Created 31 Aug 2026

VGLL4 promotes thoracic aortic aneurysm and dissection by disrupting extracellular matrix homeostasis via WISP1-mediated TIMP3/MMP9 imbalance

by Wang, Y., Ding, L., Ma, J., Diao, P., Dong, R., Tong, Y., Lai, J., Shao, Y., Hu, M., Yang, J., Jin, P., Zhang, L., Fan, X., Gong, Y., Du, C., Chen, X., Chen, X.
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Created 31 Aug 2026

A thermodynamic framework for mapping elastic recoil mechanism across the human proteome

by Desai, R., Pople, D., Musale, A., Jain, S., Sajjad, I., Wittebort, R. J., Koder, R. L., Nanda, V.
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Created 31 Aug 2026

Chemi-Proteome Language Attention Network Empowers Fragment-Based Ligand Interactome and Binding Sites Discovery with Evidence

by Liao, B., He, J., zhao, M., Cui, X., Cui, Y., Dong, C., Sun, H., Zhang, L., Zhang, J.
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Created 31 Aug 2026

FlexiTAC enables controllable PROTAC linker generation across diverse structural settings using a Bayesian flow network with posterior guidance

by Li, Y., Zhao, Y., Zhou, L., Huang, C., Xu, Q., Chen, Y., Qin, Z., Fan, K., Yang, J., Cao, D.
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Created 31 Aug 2026

Dynamic Hierarchical Interleaved Bloom Filter: An Updatable Index for Large-Scale Fast Sequence Search

by Seiler, E., Willemsen, M., Piro, V. C., Reinert, K.
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Created 31 Aug 2026

PhageTransformer - scalable and accurate host assignments for bacteriophages

by Siemers, M., Lopez, J. L., Dutilh, B. E.
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Created 31 Aug 2026

A subgenome-resolved and chromosome-scale reference genome assembly of allotetraploid wheat wild relative Aegilops peregrina

by Singh, J., Gudi, S., Maughan, P. J., Gill, U., Gupta, R.
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Created 31 Aug 2026

A Low Containment CCHFV Entry Screening Platform Identifies Compounds with Antiviral Activity against Authentic CCHFV

by Spinoza, N., N. Spector, S., R. Harmon, J., Chatterjee, P., Kainulainen, M. H., Flint, M., Borges, C., Manafi, M., Abay, T., Spengler, J. R., Bergeron, E., Spiropoulou, C. F., Hensley, L., Ozonoff, A., Farzani, T., Sabeti, P. C.
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Created 31 Aug 2026

Genome-resolved insights into microbial diversity and elemental cycling in Winogradsky columns
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Created 31 Aug 2026

PfAMA1-expressing chimeric rodent malaria parasites provide an in vivo platform for evaluating multistage interventions against malaria

by Issahaque, Q.-a., Shinzawa, N., Kegawa, Y., Sekine, T., Amino, H., Torii, M., Tsuji, M., Ishino, T.
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