Latest Research Preprints - Life Science Network

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This list contains preprints from the last 30 days only. Use the search function to access older preprints.

The default sorting of preprints in this list is by the date when the preprint was uploaded or imported to our database (shown on top). Publication date is indicated below the title.

Created 24 Aug 2026

Mycobacterium tuberculosis manipulates host inflammation and lipid metabolism through the SET1-interacting protein Rv1075c

by Coleman, A. K., Mabry, C. J., Chapman, M. J., Armijo, K. S., Smith, M. H., Huskey, J. B., Stranahan, L. W., Watson, R. O., Patrick, K. L.
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Created 24 Aug 2026

Cryo-EM structure of piscine orthoreovirus reveals structural conservation across 450 million years of viral evolution

by Okamoto, K., Munke, A., Treadaway, G. S., Sutherland, D. M., Haslene-Hox, H., Rimstad, E., Holmes, E. C., Dermody, T. S., Wessel, O.
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Created 24 Aug 2026

Engineered α-Synuclein-specific nanobody CAR iTregs restrain neuroinflammation and proteinopathy in Parkinson's disease mice

by Calderoni, A., Nannoni, M., Ruffini, G., Doglio, M., Bercher Brayer, C., Giannelli, S. G., Melki, R., Casucci, M., Bonini, C., Muggeo, S., Broccoli, V.
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Created 24 Aug 2026

Autotransporter folding avoids a kinetic trap during vectorial translocation across the bacterial outer membrane

by Yang, L., Luan, Q., Baxa, M., Clark, P. L., Gumbart, J.
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Created 24 Aug 2026

Regulation of the human voltage-gated proton channel by membrane sterols

by Han, S., Duan, R., Applewhite, S., Wang, S., Wang, G., Qian, M., Covey, D. F., Zou, X., Wang, S.
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Created 24 Aug 2026

De novo Design of Macrocyclic Molecular Glues

by Brunner, A., Wierbilowicz, K., Daumiller, D., Bexell, D., Karlsson, K., Sangfelt, O., Bryant, P.
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Created 24 Aug 2026

On the robustness of scRNA-seq foundation models for plant perturbation response prediction under cross-experiment shift

by Fernandez Burda, M., Bonazzola, R., Valli, A. A., Castrillo, G., Stegmayer, G., Ferrante, E., Milone, D. H.
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Created 24 Aug 2026

A novel benchmark dataset for enzyme function prediction reveals the limitations of state-of-the-art models

by Sartori, J., Guimaraes, A. C. R., Machado, L. d. A.
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Created 24 Aug 2026

Improved genome assemblies of plant-associated Streptomyces spp. as a resource for understanding plant pathogenicity in the genus

by Shelley, B. A., Fabian, M. L., Nguyen, H. P., Weisberg, A. J., Chang, J. H. H., Clarke, C. R.
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Created 24 Aug 2026

A Kinetochore-Associated Proteasome Pool Drives a Second Pathway of Cohesin Removal during Meiosis

by Mishra, A., Butler, R. J., Koch, L. B., Spanos, C., Severson, A. F., Marston, A. L., Boerner, G. V.
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