Preprints

Created 29 Oct 2026

Response to SMAC mimetics in patient-derived models of triple-negative breast cancer relies on RIPK1 activation

by Brown, E., Jensen, P., Yang, C.-H., Cortes Sanchez, E., Chu, Z., Yang, H., Qiao, Y., Golkowski, M., Srivastava, A., Welm, B., Fornetti, J., Welm, A. L.

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Created 29 Oct 2026

Transient Splicing-Associated Isoform Remodeling Defines Early MAPKi Resistance Adaptation in Melanoma

by Mukherjee, S., Singh, A., Patiyal, S., Joo, H., Kim, H., Pal, L. R., Wang, K., Day, C.-P., Ronai, Z. A., Ruppin, E., Hannenhalli, S.

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Created 29 Oct 2026

Optimized dosing of spatially heterogeneous radiopharmaceutical therapy reprograms poorly immunogenic tumors to enhance response to immune checkpoint blockade

by Takashima, M. E., Danaceau, Z., Bio Idrissou, M., Kwon, O., Berg, T. J., Clark, P. A., Wang, Y., Jin, W., Adeniyi, A. O., Donnelly Haasch, C., Antonelli, M., Weichert, J., Bednarz, B., Hernandez, R. T., Ong, I., Morris, Z. S.

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Created 29 Oct 2026

Spatially enforced engagement of PD-1⁺ T cells with AXL⁺ cells reprograms the tumor microenvironment and overcomes anti-PD-1 resistance

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Created 29 Oct 2026

Choline Kinase Alpha Inhibition is a Mutation Agnostic Therapeutic Vulnerability in Clonal Hematopoiesis

by Gheller, B. J., Mitchell, O., Quach, M., Gopakumar, J., Avagyan, S., Yang, S., Mathews, T. P., Haggerty, C., Meissner, A., Garcia, J., DeBerardinis, R. J., Jaiswal, S., Camargo, F., Zon, L. I.

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Created 29 Oct 2026

Multiscale, Survey-and-Target Optical Super-Resolution Histology

by Tadesse, K., Lee, O. S., Yoo, H., Ronghao, Z., Liu, Q., Chen, P., Zha, Z., Kwong, G. A., Parihar, V. C., Robertson, J., Robinson, B., Chou, E., Jia, S.

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Created 29 Oct 2026

Liquid-state surface fermentation as a platform for pure mycelium materials production

by Saluena Martin, J., Dimitriadis, P., Attalibi, S., Sangosanya, A. O., Philippini, R., Alavijeh, R. S., Brancart, J., Elsacker, E., Peeters, E.

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Created 29 Oct 2026

Low-Cost Real-Time Fiber-Optic Distance Sensing for OPM-based Biomagnetic Measurements

by Huebner, M., Marquetand, J., Yang, H.

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Created 29 Oct 2026

Ultrasonic Detection of Venous Gas Emboli and Tissue Gas in Rodents: Toward Imaging Biomarkers for Decompression Stress

by Currens, J. B., Eltz, K. M., Sellers, R. S., Dugrenot, E., Papadopoulou, V.

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Created 29 Oct 2026

Megalin-mediated deterministic pseudotransduction in proximal tubules fundamentally challenges current understanding of AAV kidney transduction

by Sairavi, A., Das, R., Li, L., Groat, T., Matsuzaki, Y., Hirai, H., Hutchens, M., Nakai, H.

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