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Created 30 Sep 2026
Biosynthetic origin of anticancer dolastatin 15 reveals a noncanonical NRPS architecture enabling 2-keto acid activation.
by Manyun Chen, Jie Liu, Hsin-Ying Tsai, Cheng-Yu Li, Jeremiah D Batucan, Campbell W Eckhardt, Tam H D Pham, Emma K Ellis, Ranjala Ratnayake, Valerie J Paul, Steven D Bruner, Mohamed S Donia, Hendrik Luesch, Yousong Ding — Proceedings of the National Academy of Sciences of the United States of America. Volume 123(40): e2615454123. Oct 06, 2026.
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Created 30 Sep 2026
SRSF3 plays a key role in liver cancer sex disparity by facilitating hepatocyte expression of ERα and FOXA.
by Lulu Yu, Masahiko Ajiro, Vladimir Majerciak, Alexei Lobanov, Yafeng He, Maggie Cam, Baktiar Karim, Deanna Gotte, Chuxia Deng, Keji Zhao, Douglas R Lowy, Nicholas J G Webster, Zhi-Ming Zheng — Proceedings of the National Academy of Sciences of the United States of America. Volume 123(40): e2536317123. Oct 06, 2026.
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Created 30 Sep 2026
TCR-mTORC1 signaling promotes epigenetic stabilization of Foxp3 expression in regulatory T cells via TET protein translation.
by Tomohide Kinoshita, Akira Nakajima, Toru Kobayashi, Mai Ohno, Yuxi Wei, Tatsumasa Hasegawa, Norihito Hayatsu, Shoshiro Hirayama, Yu-Ichi Tsukada, Atsushi Hirao, Shigeo Murata, Shohei Hori — Proceedings of the National Academy of Sciences of the United States of America. Volume 123(40): e2612904123. Oct 06, 2026.
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Created 30 Sep 2026
Associative synaptic plasticity creates dynamic persistent activity.
by Albert J Wakhloo, David G Clark, L F Abbott — Proceedings of the National Academy of Sciences of the United States of America. Volume 123(40): e2526156123. Oct 06, 2026.
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Created 30 Sep 2026
Desulfinylation of the deubiquitinase USP7 by SRXN1 attenuates oxidative acute liver injury.
by Mengyun Ke, Jong-Won Kim, Meishu Xu, Jingyuan Wang, Lingyi Liu, Syamprasad N P, Bin Yang, Xiaofei Wang, Huatian Li, Songrong Ren, Kate S Carroll, Song Li, Wen Xie — Proceedings of the National Academy of Sciences of the United States of America. Volume 123(40): e2620180123. Oct 06, 2026.
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Created 30 Sep 2026
Chain organization of dimple-ended magnetite magnetosomes supports field-dependent cell linking in unicellular magnetotactic bacteria.
by Jinhua Li, Yuqin Wang, Peiyu Liu, Qianqian Lan, Xiang Zhao, Nicolas Menguy, Jian Wang, Eric Leroy, Jiawei Liu, Rafal E Dunin-Borkowski, Wyn Williams, Andrew P Roberts, Rixiang Zhu, Yongxin Pan — Proceedings of the National Academy of Sciences of the United States of America. Volume 123(40): e2615054123. Oct 06, 2026.
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Created 30 Sep 2026
Loss of CsrA in Acinetobacter baumannii leads to lethal dysregulation of alanine metabolism.
by Rosa L Sava, Michael J Gebhardt — Proceedings of the National Academy of Sciences of the United States of America. Volume 123(40): e2624702123. Oct 06, 2026.
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Created 30 Sep 2026
Reproducible cortical links between functional hierarchy, structure, and metabolism.
by Dardo Tomasi, Nora D Volkow — Proceedings of the National Academy of Sciences of the United States of America. Volume 123(40): e2614926123. Oct 06, 2026.
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Created 30 Sep 2026
Functional brain networks underlying approach-avoidance conflict processing in humans and rats.
by Norman R Stewart, Sabrina L Valenzano, Jingmin Zhang, Sonja Chu, Zhemeng Wu, Jina Khiabani Javid, Andy C H Lee, Rutsuko Ito — Proceedings of the National Academy of Sciences of the United States of America. Volume 123(40): e2601203123. Oct 06, 2026.
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Created 30 Sep 2026
The phenotypic landscape of the model firmicute Bacillus subtilis.
by Lili M Kim, Byoung-Mo Koo, Hannah N Burkhart, Daniela Vollmer, Waldemar Vollmer, Horia Todor, Carol A Gross — Proceedings of the National Academy of Sciences of the United States of America. Volume 123(40): e2619440123. Oct 06, 2026.
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