Latest Research Publications - Life Science Network

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Created 21 Oct 2026

AI-guided design and biomaterial integration for next-generation extracellular vesicle therapeutics: an evidence-weighted translational framework.

by Jiaqi Tian, Qiang Li, Ning Li, Dandan Song, Zengfeng Li, Xiaotan Shi, Huiyu Sun, Shuyin Duan, Lin Zhang — Journal of nanobiotechnology. Volume 24(1). Jul 25, 2026.
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Created 21 Oct 2026

HAMA microneedles patch loaded with muscle-targeting engineered apoptotic vesicles and attenuating sarcopenia by regulating mitochondrial homeostasis.

by Jiayao Zhang, Zhao Lin, Haiqi Ding, Mingjuan Zhang, Yibin Su, Linhai Yang, Dingqiang Chen, Xuanhao Chen, Jun Luo, Fuli Wen, Guoyu Yu, Zineng Yan, Jie Xu — Journal of nanobiotechnology. Volume 24(1). Jul 24, 2026.
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Created 21 Oct 2026

P4HA1⁺ collagen-modifying fibroblasts are associated with pro-tumor niches and therapeutic vulnerabilities in colorectal cancer.

by Kai Gui, Yan Chen, Qinqin Du, Ke Lv, Weitao Wang, Ziyun Li, Yuhang Cheng, Wenyan Wu, Min Tang, Cheng Zhang, Li Wang — Journal of translational medicine. Volume 24(1). Jul 24, 2026.
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Created 21 Oct 2026

Metabolic plasticity underlies ferroptosis resistance driven by mutant p53 in pancreatic ductal adenocarcinoma.

by Adriana Celesia, Filippo Piccoli, Tian Wang, Yushu Hu, Federica Danzi, Antonino Aparo, Barbara Cisterna, Raffaella Pacchiana, Maria Poles, Maria Teresa Scupoli, Claudio Luchini, Stefano Ugel, Massimo Donadelli, Alessandra Fiore — Molecular cancer. Volume 25(1). Jul 23, 2026.
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Created 21 Oct 2026

Parkinson's disease LRRK2 mutations dysregulate iron homeostasis and promote oxidative stress and ferroptosis in human neurons and astrocytes.

by Adamantios Mamais, Richard D Batchelor, Aravindraja Chairmandurai, Thomas B Ladd, Austin J Shute, Nitya Subrahmanian, Nunziata Maio, Christopher D Vulpe, Matthew J LaVoie — Molecular neurodegeneration. Volume 21(1). Jul 24, 2026.
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Created 21 Oct 2026

Epigenetic modulation of NKG2D ligands enhances NKG2D-CAR T cell efficacy in neuroblastoma.

by Alfonso Navarro-Zapata, María Octavia De Santisteban, Rita María Regojo-Zapata, Marta Ibáñez-Navarro, Laura Clares-Villa, Marta de la Hoz, Andrea Romero, Carmen Mestre-Durán, Karima Al-Akioui Sanz, Halin Bareke, Sara Naharro, Jordi Minguillón, Lidia Pertíñez, Natalia Riestra, Mireia Masot, Carla Martín-Cortázar, Cristina Aguirre-Portolés, Cristina Ferreras, Adriana Mañas, Antonio Pérez-Martínez, Lucía Fernández Casanova — Journal of translational medicine. Volume 24(1). Jul 24, 2026.
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Created 21 Oct 2026

Ribosome biogenesis and selective translational control as oncogenic vulnerabilities in hematologic malignancies.

by Juan Luiz Coelho-Silva, João Agostinho Machado-Neto — Molecular cancer. Volume 25(1). Jul 23, 2026.
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Created 21 Oct 2026

High xCT expression indicates poor prognosis and chemoradiotherapy resistance in rectal cancer patients.

by Yingru Li, Heng LiuFu, Zhilong Yuan, Wenchang Gan, Shaoyong Peng, Jinhong Li, Haiyang Xin, Canfeng Cai, Bing Zeng — Cancer cell international. Volume 26(1). Jul 25, 2026.
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Created 21 Oct 2026

ASH2L-mediated H3K4me3 methylation governs palatal development by regulating WNT5B.

by Zhichen Ling, Xueqin Zhu, Xinyi Tan, Zhangke Ma, Furong Xie, Jun Wang — Epigenetics & chromatin. Volume 19(1). Jul 24, 2026.
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Created 21 Oct 2026

S. carcinoma arising in a breast implant: a case report and review of the literature.

by Gustavo Adolfo Villegas-Gomez, Valentina Pérez-Ariza, Marcela Mejía-Arango, María Isabel Rizo — Journal of medical case reports. Volume 20(1). Jul 24, 2026.
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