Latest Research Publications - Life Science Network

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Created 06 Aug 2026

A metabolite morphogen coordinates multicellular development in Bacillus subtilis.

by Taylor B Updegrove, Vani Pande, Fukang She, Michael C Gilmore, Vivek Anantharaman, David M Stevenson, Daniel Amador-Noguez, L Aravind, Felipe Cava, Jiji Chen, Jue D Wang, Kumaran S Ramamurthi — Science advances. Volume 12(32): eaee6610. Aug 07, 2026.
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Created 06 Aug 2026

Failed metabolic adaptation to stress contributes to epidermal cell adhesion defects in Darier disease.

by Robert M Harmon, Erin F McCarthy, Annette Krol, Aashutosh Shetti, Jonas Braun, Rosemary J DiDominicis, Lisa Godsel, Ziyou Ren, Bethany E Perez White, Eran Cohen-Barak, Roni Dodiuk-Gad, Johann E Gudjonsson, Amy S Paller, Cory L Simpson, Samuel Weinberg, Russell Dahl, Yogesh Goyal, Murali Prakriya, Kathleen J Green — Science advances. Volume 12(32): eaee1599. Aug 07, 2026.
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Created 06 Aug 2026

Renoprotective effects of tubular glucagon receptor activation mediated by V-ATPase.

by Hua Qu, Mingyue Xu, Pan Du, Linlin Zhang, Wensi Wang, Xiufei Liu, Jiaran Zhu, Chenfu Tian, Qingshan He, Ju Li, Yiwen Tao, Zhengyuan Gong, Qingwu Yang, Yi Zheng, Hongting Zheng — Science advances. Volume 12(32): eaeg2534. Aug 07, 2026.
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Created 06 Aug 2026

Vimentin remodeling in response to oxidants and electrophiles is modulated by pH.

by Alma E Martínez, Paula Martínez-Cenalmor, Patricia González-Jiménez, Cristina Vidal-Verdú, María A Pajares, Dolores Pérez-Sala — Science advances. Volume 12(32): eaed9655. Aug 07, 2026.
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Created 06 Aug 2026

Biophysical reprogramming of immunosuppressive neutrophils by cold atmospheric plasma reinvigorates antitumor immunity.

by Ganyu Wang, Zhiwei Cui, Xin Jiang, Ying Sun, Yifan Liu, Xinyuan Li, Wushan Li, Ruirui Sun, Xuemei Liu, Nengwang Yu, Xiaolong Wang, Benkang Shi, Weiqiang Jing — Science advances. Volume 12(32): eaee2483. Aug 07, 2026.
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Created 06 Aug 2026

Cohesin facilitates nucleosome invasion by transcription factors.

by Shane Stoeber, Hengye Chen, Ruo-Wen Chen, Courtney Smith, Sam Becker, Sarah Vinson, Michael G Poirier, Lu Bai — Science advances. Volume 12(32): eaef1603. Aug 07, 2026.
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Created 06 Aug 2026

SARS-CoV-2 nucleocapsid induces hyperinflammation and vascular leakage through the Toll-like receptor signaling axis in macrophages.

by Zhenlan Yao, Pablo A Alvarez, Carolina Chavez, Yennifer Delgado, Prashant Kaushal, David W Buchholz, David Austin, Qian Li, Yanying Yu, Anne K Zaiss, Vaithilingaraja Arumugaswami, Qiang Ding, Jeffrey J Hsu, Robert Damoiseaux, Hector C Aguilar, Mehdi Bouhaddou, Alexander Hoffmann, Melody M H Li — Science advances. Volume 12(32): eaea2780. Aug 07, 2026.
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Created 06 Aug 2026

Multi-component gradients in 3D host frameworks enabled stack-type zinc plating/stripping for highly durable aqueous Zn-ion batteries.

by Jingjie Sun, Tianyu Shen, Mingyue Zhang, Yizhi Xing, Jie Wei, Qianchuan Yu, Zuoxiu Tie, Zhong Jin — Science advances. Volume 12(32): eaeh4699. Aug 07, 2026.
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Created 06 Aug 2026

Development of a structurally distinct TopBP1 inhibitor that enhances PARP blockade and reverses osimertinib resistance.

by Fang-Tsyr Lin, Shwu-Jiuan Lin, Kang Liu, Yang Xiao, Lidija A Wilhelms Garan, Helena Folly-Kossi, Weei-Chin Lin — Science advances. Volume 12(32): eaeg1996. Aug 07, 2026.
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Created 06 Aug 2026

Leveraging IGF signaling to improve the spatial organization and regenerative potential of iPSC-derived vascularized liver organoids.

by Da-Hyun Kim, Yongju Lee, Min-Ji Kim, Amos Chungwon Lee, Sunghoon Kwon, Kyung-Sun Kang — Science advances. Volume 12(32): eaea3814. Aug 07, 2026.
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