Latest Research Publications - Life Science Network

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Created 18 Oct 2026

Misplaced DNA sensing in intervertebral disc degeneration: mitochondrial stress, sterile inflammation, pyroptosis, and DNA clearance.

by Hongtao Li, Jiacheng Zheng, Guangyi Yang, Bochen Peng, Hanbin Liu, Liguo Zhu, Changxiao Han, Minshan Feng — Inflammation research : official journal of the European Histamine Research Society ... [et al.]. Volume 75(1). Oct 17, 2026.
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Created 18 Oct 2026

Liver-specific amino acid metabolism impacts on efficacy of cancer immunotherapy.

by Yuma Fukumoto, Fumiaki Mukohara, Momoko Iwatsuru, Youki Ueda, Hiroaki Kanzaki, Sadahisa Ogasawara, Jason Lin, Masahito Kawazu, Toshifumi Ninomiya, Naoya Kemmotsu, Joji Nagasaki, Shinichi Toyooka, Tsuyoshi Osawa, Takamasa Ishino, Yosuke Togashi — Oncogene. Oct 17, 2026.
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Created 18 Oct 2026

Phosphorylation of IRS4 at YY111/112 promotes LUSC progression via PI3K/AKT pathway activation.

by Yilixiati Aihemaiti, Qiuhan Ren, Xiangling Jiang, Kaideya Wushaying, Ran Chen, Yanli Wang, Xian Zhao, Lei Xu, Zhi Yang, Jianxiu Yu, Jian Huang — Oncogene. Oct 17, 2026.
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Created 18 Oct 2026

Multimodal substrate recruitment enables CTLH^MKLN1 E3 ligase to target acetylated N-, C-, and internal degrons.

by Sara Sepic, Karthik V Gottemukkala, Jiale Du, Samuel A Maiwald, Jakub Chrustowicz, Eleftheria C Papadopoulou, Luca J Stier, Susanne von Gronau, Brenda A Schulman — Nature communications. Volume 17(1). Oct 17, 2026.
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Created 18 Oct 2026

Difluoromethylornithine modulates mutant K-RAS signaling pathways in pancreatic cancer cells.

by Hwudaurw Chen, David E Stringer, Haiyan Cui, Eugene W Gerner, Natalia A Ignatenko — Amino acids. Volume 58(1). Sep 16, 2026.
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Created 18 Oct 2026

Modulation of the FAK-Src Signalling Axis by Oncoviruses: Molecular Mechanisms, Functional Consequences, and Therapeutic Opportunities.

by Yasmeen A Albalawi, Afnan O Deebani, Horeyah Mohammed Almadani, Bian K Almessiry, Zuhair M Mohammedsaleh, Aaishah M H Kaabi, Ahmed M Abdulfattah, Rasha Assad Assiri — Reviews in medical virology. Volume 36(6): e70214.
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Created 18 Oct 2026

Adjuvant Systemic Therapies After Nephrectomy for Renal Cell Carcinoma: A Bayesian Network Meta-Analysis and Multi-Criteria Benefit-Risk Assessment.

by Shugo Yajima, Gaku Okumura, Soichiro Yoshida, Hiroshi Fukushima, Hiroyuki Sato, Akihiro Hirakawa, Toshiki Kijima, Hitoshi Masuda, Yasuhisa Fujii — Targeted oncology. Oct 18, 2026.
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Created 18 Oct 2026

Light quality shapes mesophyll conductance in cucumber leaves in association with coordinated anatomical changes.

by Xin Tian, Qinglin Guo, Han Zhang, Xinlan Luo, Jiarui Lu, Liang Zheng — Photosynthesis research. Volume 164(6). Oct 17, 2026.
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Created 18 Oct 2026

Statistical optimization of melanin-like pigment biosynthesis by marine Streptomyces isolate MOE3 and evaluation of its cytotoxic activity against A-431 cells.

by Moaz M Hamed, Sahar W M Hassan, Eman H Zaghloul — BMC microbiology. Volume 26(1). Oct 17, 2026.
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Created 18 Oct 2026

Attenuation of cyclophosphamide toxicity by protective effects of curcumin in albino rats model.

by Noura Mohammed Bakr, Abeer Abdel Maksoud, Nehad Abdelmawgoud Ahmad — BMC oral health. Volume 26(1). Oct 07, 2026.
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