Latest Research Publications - Life Science Network

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Created 15 Jun 2026

Design, synthesis, antibacterial activity evaluation, and mechanism of action study of novel pyrrolidine derivatives containing sulfonamide structures.

by Tonghong Xia, Laiqi Li, Xinyu Wang, Jianhong Li, Yazhen Chen, Lei Yu, Xiaokang Lv, Song Bai — Molecular diversity. Jun 15, 2026.
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Created 15 Jun 2026

Integrating machine learning-based molecular design with experimental validation for the discovery of EGFR inhibitors in lung cancer.

by Hailing Qie, Liyuan Wang, Ce Li, Chen Wu, Yong Wang, Kuo Xiao, Lili Diao — Molecular diversity. Jun 15, 2026.
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Created 15 Jun 2026

Guanidinium-rich scyllo-inositol molecular transporter enables enhanced transdermal and intracellular delivery of vitagen.

by Nasim Sepay, Soojeong Yoon, Seok-Ho Yu, Jungkyun Im — Drug delivery and translational research. Jun 15, 2026.
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Created 15 Jun 2026

Sphingosine kinase 1 is dysregulated via hypoxia-inducible factor 1α in oral squamous cell carcinoma.

by Ritu Pandey, Supriya Vishwakarma, Vikas Gupta, Neha Arya, Saikat Das, Rashmi Chowdhary, Ashok Kumar — The Indian journal of medical research. Volume 163(6): 701-709.
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Created 15 Jun 2026

Dynamics of Singlet Fission in the TIPS-Pn Cluster: Endothermic or Exothermic?

by Haoxian Huang, Man Shi, Yang Ni, Shengyang Chen, Xianfeng Qiao, Dongge Ma — The journal of physical chemistry letters. Jun 15, 2026.
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Created 15 Jun 2026

HLA-DR⁺ Schwann Cells Generate the Protumor Cancer-Neuron-Immune Niche in Head and Neck Squamous Cell Carcinoma.

by Xiaoyan Meng, Zhonglong Liu, Shijian Zhang, Luoman Gan, Liren Cao, Jingjing Sun, Lingfang Zhang, Yue He — Advanced science (Weinheim, Baden-Wurttemberg, Germany). Pages e76131. Jun 15, 2026.
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Created 15 Jun 2026

Tumor Microenvironment-Responsive Nanoreactor Induces Disulfidptosis in Pancreatic Cancer via Metabolic Interference and Redox Catalysis.

by Rui Fu, Qing Li, Guanzhong Zhao, Qingyan Gao, Huantong Chen, Khemayanto Hidayat, Jiaying Xu, Liqiang Qin, Chunhong Hu, Yu Chong, Su Hu — Advanced science (Weinheim, Baden-Wurttemberg, Germany). Pages e76146. Jun 15, 2026.
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Created 15 Jun 2026

Single-Cell RNA Editing Identifies T Cell ADAR1 as a Key Regulator of Immune Exhaustion and Anti-PD-1 Resistance in Colorectal Cancer.

by Da Kang, Song-Zuo Xie, Yong-Zhou Luo, Xin-Pei Deng, Xi-Rong Tan, Ze-Geng Chen, Ling-Xing Zeng, Gong Chen, Pei-Rong Ding, Zhi-Zhong Pan, Rong-Xin Zhang — Advanced science (Weinheim, Baden-Wurttemberg, Germany). Pages e76143. Jun 15, 2026.
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Created 15 Jun 2026

Engineered Exosomal miR-146a-5p Reprograms BMSC Fate and Restores Mitochondrial Homeostasis in Glucocorticoid-Induced Osteonecrosis of Femoral Head.

by Zehui Lv, Xuejie Cai, Yiming Xu, Xingdong Yang, Ruoying Wang, Han Wang, Yixin Bian, Jiawei Xu, Jiao Lu, Lulu Liu, Yingjie Wang, Jibin Song, Bin Feng, Xisheng Weng — Advanced science (Weinheim, Baden-Wurttemberg, Germany). Pages e75897. Jun 15, 2026.
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Created 15 Jun 2026

Thymosin Alpha-1 Restores Chemotherapy-Induced Antitumor Immunity by Chaperoning a MicroRNA Ligand of TLR7 in Dendritic Cells.

by Yiting Wei, Jing Chen, Yunpeng Zhang, Yueming Liu, Fengjiao Zhu, Xuru Wang, Xiaohe Zhou, Chengdong Wu, Wenqi Zhang, Jinpeng Chen, Yuchen Zhang, Ning Pan, Kang Chen, Shiya Zheng, Chunguang Yan, Ling Liu, Lixin Wang — Cancer research. Jun 15, 2026.
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