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Created 07 Sep 2026

Integrating Tumor Targeting and Half-Life Extension into a Dual-Surfaced Single-Domain ADAPT Protein.

by Emma Larsson, Moeen Ud-Din, Athanasios Bitzios, Enrique Recasens Pérez-Vera, Hanna Tegel, Anna Orlova, Vladimir Tolmachev, Anzhelika Vorobyeva, Sophia Hober — Molecular pharmaceutics. Volume 23(9): 4743-4757. Sep 07, 2026.
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Created 07 Sep 2026

Betaine-Modified Chitosan Nanoparticles Enhance Oral Insulin Delivery via pH-Triggered Charge Switching, Mucus Penetration, and Lysosomal Escape.

by ShengQin Chen, JinQi Wang, Yang Liu, QingYa Miao, XiuYuan Rong, Jia Yang — Molecular pharmaceutics. Volume 23(9): 4482-4498. Sep 07, 2026.
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Created 07 Sep 2026

Preclinical Evaluation of [68Ga]Ga-CS03 as a Novel GPC3-Targeted Probe for Imaging GPC3 in Hepatocellular Carcinoma Models.

by Dai Shi, Wujian Mao, Yutao Xie, Pan Zhou, Minqiang Hu, Qingyu Lin, Yuxia Liu, Dengfeng Cheng — Molecular pharmaceutics. Volume 23(9): 4710-4718. Sep 07, 2026.
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Created 07 Sep 2026

A Cosmetic Product Containing PEG Derivatives Induces Anti-PEG IgM Mainly through Stimulation of the Spleen Cells in Mice.

by Yuri Kim, Haruka Takata, Shingo Kobayashi, Hidenori Ando, Tatsuhiro Ishida — Molecular pharmaceutics. Volume 23(9): 4673-4680. Sep 07, 2026.
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Created 07 Sep 2026

Self-Assembling Synthetic Trehalose Glycolipids for Mincle Activation: Biophysical Properties, Molecular Dynamics Simulations, and Vaccine Adjuvant Activity.

by Walid M Abdelwahab, Kristopher K Short, Alexander Riffey, Thomas M Weiss, Cassie Buhl, Tamer A Elwaie, Asia Marie S Riel, David Holley, Kendal T Ryter, Shannon M Miller, Jay T Evans, David J Burkhart — Molecular pharmaceutics. Volume 23(9): 4466-4481. Sep 07, 2026.
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Created 07 Sep 2026

Unnatural Amino Acid Substitutions to Improve In Vivo GRPR-Targeting Capability of [68Ga]Ga-SP01011 for Cancer Imaging.

by Sheetal Pathania, Chao-Cheng Chen, Pauline Ng, Helen Merkens, Wing Sum Lau, Joseph Lau, François Bénard, Kuo-Shyan Lin — Molecular pharmaceutics. Volume 23(9): 4770-4781. Sep 07, 2026.
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Created 07 Sep 2026

Payload-Free [89Zr]Zr-DFO*-sq-Enfortumab ImmunoPET for Imaging Nectin-4 Expression in Bladder Cancer.

by Marian N Aziz, Tianyuan Wang, Jiawen Lang, Mickey Glover, Abhilash Boppana, Sashi Debnath, Jui Wan Loh, Jeon Lee, Sean Yan, Ningyan Zhang, Xiankai Sun, Jer-Tsong Hsieh, Jue Wang, Li Liu, Guiyang Hao — Molecular pharmaceutics. Volume 23(9): 4758-4769. Sep 07, 2026.
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Created 07 Sep 2026

Engineered Natural Killer Cell Derived-Extracellular Vesicles: An Acellular Immunotherapy with Cytotoxic Effects in SNU-1079 Human Cholangiocarcinoma Cells.

by Piyush Gondaliya, Dylan A Zinn, Adil Ali Sayyed, Julia Driscoll, Irene K Yan, Nadia Mensali, Sébastien Wälchli, Tushar Patel — Molecular pharmaceutics. Volume 23(9): 4540-4552. Sep 07, 2026.
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Created 07 Sep 2026

Evaluation of 18F-FPPA as a Positron Emission Tomography Radioligand for Imaging CSF1R in LPS-Induced Rat Model of Neuroinflammation.

by Zhequan Fu, Qingyu Lin, Zhenwei Wang, Hongxing Su, Zhoumi Hu, He Zhang, Rong Sheng, Cheng Wang, Dengfeng Cheng — Molecular pharmaceutics. Volume 23(9): 4571-4578. Sep 07, 2026.
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Created 07 Sep 2026

Targeted Delivery of Carvacrol via TPGS-Tf-Polydopamine Nanoconjugate Scaffold on TNBC Tumor Xenograft for Understanding In Vivo Tumor Dynamics and 3D Cancer Spheroid Model, Mimicking a Tumor Environment.

by Rumi Mahata, Sounik Manna, Dibyendu Giri, Ananya Pradhan, Rathindranath Baral, Biswajit Saha, Sujata Maiti Choudhury — Molecular pharmaceutics. Volume 23(9): 4510-4523. Sep 07, 2026.
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