Latest Research Publications - Life Science Network

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Created 29 Aug 2026

Hi-Cformer enables multiscale chromatin contact map modeling for single-cell Hi-C data analysis.

by Xiaoqing Wu, Zian Wang, Rui Jiang, Xiaoyang Chen — Science advances. Volume 12(35): eaeg0134. Aug 28, 2026.
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Created 29 Aug 2026

Neuron-derived SPP1 instructs microglia to limit degeneration.

by Song Li, Tatjana C Jakobs — Science advances. Volume 12(35): eaee4940. Aug 28, 2026.
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Created 29 Aug 2026

Structure-function analysis of the FCRL5-IgG1 Fc complex reveals an unappreciated pathway for B cell modulation by Fc-attenuated IgG.

by Bart M Herpers, Mo Guo, Sanghwan Ko, George Delidakis, Jin Eyun Kim, Chang-Han Lee, Mohamed I Gadallah, Jennifer S Brodbelt, Y Jessie Zhang, George Georgiou — Science advances. Volume 12(35): eaei1233. Aug 28, 2026.
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Created 29 Aug 2026

Programmable protein degraders enable selective knockdown of pathogenic β-catenin subpopulations in vitro and in vivo.

by Tianzheng Ye, Azmain Alamgir, Cara M Robertus, Darianna Colina, Connor Monticello, Thomas Connor Donahue, Chandra Bandi, Lauren Hong, Sophia Vincoff, Shrey Goel, Kieu Lam, James Heyes, David Putnam, Christopher A Alabi, Pranam Chatterjee, Matthew P DeLisa — Science advances. Volume 12(35): eaec8271. Aug 28, 2026.
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Created 29 Aug 2026

SHARPIN restrains IL-33 release by stromal cells to control ILC2 inflammation.

by Peng Zeng, Xin Mao, Wen Zhang, Jia Li, Zhiqing Wang, Chao Zhang, Qian Li, Yun-Cai Liu — Science advances. Volume 12(35): eaea2388. Aug 28, 2026.
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Created 29 Aug 2026

scProtoTransformer: Scalable reference mapping across molecules, cells, and donors.

by Zhenchao Tang, Haohuai He, Shouzhi Chen, Jun Zhu, Tianxu Lv, Jiale Zhou, Jiehui Huang, Yaokun Li, Guanxing Chen, Linlin You, Calvin Yu-Chian Chen — Science advances. Volume 12(35): eaef0286. Aug 28, 2026.
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Created 29 Aug 2026

Adipose-cartilage communication via EV-Mito-mtDNA signaling promotes osteoarthritis progression.

by Cheng Gu, Fawei Liao, Ganggang Kong, Shiyi Yin, Yifei Jiang, Runtao Zhou, Jingguang Zeng, Yixun Wu, Xubo Li, Bo Wang, Qiguang Pang, Ming Fu, Qingtang Zhu, Canbin Zheng — Science advances. Volume 12(35): eaee6780. Aug 28, 2026.
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Created 29 Aug 2026

O-Glycosylated expansin ThSWO condensates drive Trichoderma harzianum attachment to rice root during the colonization process.

by Chen Chen, Xiaoteng Shi, Han Zhu, Tuokai Wang, Bozheng Lin, Yajing Gu, Haiyang Guo, Yanxia Ru, Jiahao He, Ruisuhua Liang, Linhua Cao, Tuo Li, Waseem Raza, Yaowang Li, Dongyang Liu, Qirong Shen — Science advances. Volume 12(35): eaef7536. Aug 28, 2026.
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Created 29 Aug 2026

LATS1/2 inactivation drives a distinct venous endothelial cell response that contributes to fibrotic remodeling of the lung.

by Konstantinos Kontodimas, Ahmed A Raslan, Benjamin Spira, Crystal Zhu, Janardhan Karapurkar, Yohana Kefella, Darren Chiu, Xintao Qiu, Jennifer E Beane, Giovanni Ligresti, Xaralabos Varelas — Science advances. Volume 12(35): eaef8468. Aug 28, 2026.
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Created 29 Aug 2026

SpotMAX: A generalist framework for multidimensional automatic spot detection and quantification.

by Francesco Padovani, Ivana Čavka, Ana Rita Rodrigues Neves, Cristina Piñeiro López, Nada Al-Refaie, Leonardo Bolcato, Dimitra Chatzitheodoridou, Yagya Chadha, Pablo Lagos, Timon Stegmaier, Xiaofeng A Su, Jette Lengefeld, Daphne S Cabianca, Simone Köhler, Kurt M Schmoller — Science advances. Volume 12(35): eadw3811. Aug 28, 2026.
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