Latest Research Publications - Life Science Network

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Created 11 Aug 2026

Insulin receptor substrate 2 (IRS2) confers resistance to PI3K pathway inhibition in PIK3CA mutant breast cancer.

by Michael W Lero, Jennifer S Morgan, Michael-Anthony Card, Lihua Julie Zhu, Junhui Li, Rui Li, Quyen Thu Bui, Emma Mohlmann, Hira L Goel, Leslie M Shaw — The Journal of biological chemistry. Pages 113426. Aug 10, 2026.
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Created 11 Aug 2026

Activation of pro-survival autophagy by a small molecule promoting p62 oligomerisation.

by Johan Panek, Edward Fielder, Congsing Sun, Steph Crabtree, Tetsushi Kataura, Niall Wilson, Lakshana Baheerathan, Jiangyu Tang, Laura Booth, Wyatt Yue, Gavin Richardson, Lauren Holder, Gavin J Miller, Jóhannes Reynisson, Sovan Sarkar, Viktor I Korolchuk — The Journal of biological chemistry. Pages 113430. Aug 10, 2026.
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Created 11 Aug 2026

ATR-dependent phosphorylation of the histone acetyltransferase HBO1 suppresses chromatin binding and promotes replication stress responses.

by Chunyan Zong, Jiamin Zhang, Zhe Zhang, Yujuan Cai, Yiran Wang, Yan Fang, Guopei Zheng, Qian Li, Lulu Wang, Jianfeng Shen — The Journal of biological chemistry. Pages 113419. Aug 10, 2026.
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Created 11 Aug 2026

A ternary association of KRas, EphA2 and integrins controls PDAC cell behaviour.

by Mahak Fatima, Nasir Haider, Stuart A Cain, Bipul R Acharya, Megan R Chastney, Junzhe Zha, Matthew C Jones, Stacey Warwood, David Knight, Derek A O'Reilly, Jonathan D Humphries, Benjamin T Goult, Claus Jørgensen, Martin J Humphries — The Journal of biological chemistry. Pages 113421. Aug 10, 2026.
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Created 11 Aug 2026

Nivolumab plus chemotherapy or ipilimumab versus chemotherapy as first-line treatment for advanced esophageal squamous cell carcinoma: 5-year follow-up results from CheckMate 648.

by K Kato, J Ajani, Y Doki, J Xu, L Wyrwicz, S Motoyama, T Ogata, H Kawakami, C-H Hsu, A Adenis, F El Hajbi, M Di Bartolomeo, M Ignez Braghiroli, E Holtved, T Makino, M Blum Murphy, J Zhang, P Sharma, B He, M Lei, Y Matsumura, Y Kitagawa, I Chau — Annals of oncology : official journal of the European Society for Medical Oncology. Aug 10, 2026.
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Created 11 Aug 2026

Exploring the Putative Role of EGFR in Prostate Cancer: Interactions with Androgen and Estrogen Receptors.

by G M Gonçalves, D S Souza, Crm Costa, Meg Oliveira, C S Porto, C M Vicente — The Journal of steroid biochemistry and molecular biology. Pages 107101. Aug 10, 2026.
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Created 11 Aug 2026

Long-term risk of metachronous gastric neoplasms after curative endoscopic submucosal dissection for early gastric cancer.

by Jong Sun Park, Eunyoung Angela Lee, Ji Hyun Park, Bumhee Park, Jong Hoon Park, Min Jae Yang, Sun Gyo Lim, Sung Jae Shin, Sung Soo Ahn, Gil Ho Lee, Choong-Kyun Noh — Endoscopy. Aug 10, 2026.
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Created 11 Aug 2026

Health Care and Social Service Utilization Before, During, and After the COVID-19 Pandemic: An Integrated Data Analysis.

by Carlene A Mayfield, Liping Tong, Rachel George, Kailas Venkitasubramanian, Angelica Mejia, Kristie Foley — Journal of public health management and practice : JPHMP. Aug 07, 2026.
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Created 11 Aug 2026

Cross-Sector Integration of Clinical and Social Service Data During COVID-19: Implementation of a Regional Integrated Data System Partnership.

by Carlene A Mayfield, Rachel George, Liping Tong, Kailas Venkitasubramanian, Kristie Foley, Julie Wittmer, Angelica Mejia, Kinneil Coltman — Journal of public health management and practice : JPHMP. Aug 07, 2026.
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Created 11 Aug 2026

Encephalopathy Post CAR-T Cell Therapy in Relapsed/Refractory Multiple Myeloma: Beyond ICANS.

by Rita Ahmad, Mackenzie Wild, Tyler Friesen, Michael Hall, Sammantha Kouba, Seth Maliske — Journal of investigative medicine high impact case reports. Volume 14: 23247096261478903. Epub Aug 10, 2026.
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