Latest Research Publications - Life Science Network

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Created 22 Aug 2026

An in silico framework for dissecting the mechanistic origins of in vivo recorded neuronal activity.

by Bjorge Meulemeester, Arco Bast, María Royo, Rieke Fruengel, Su Saka, Foivos Kastrinakis, Marcel Oberlaender — PLoS computational biology. Volume 22(8): e1014617. Aug 21, 2026.
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Created 22 Aug 2026

Emergence of a novel GII.17 variant is associated with immune evasion rather than an altered HBGA-binding profile.

by Stefan T van der Krieken, Francisco Morais Esteves, Nele Villabruna, Claudia M E Schapendonk, Ray W Izquierdo-Lara, Putri Ayu Fajar, Lonneke Leijten, Anja de Jong, Roman I Koning, Michail C Doukas, Corine H Geurts van Kessel, Marion P G Koopmans, Miranda de Graaf — PLoS pathogens. Volume 22(8): e1014522. Aug 21, 2026.
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Created 22 Aug 2026

Antigen-experienced airway CD8⁺ effector memory T cells promote a detour pathway for mycobacterial killing in the spleen.

by Julia Seifert, Visai Muruganandah, Socorro Miranda-Hernandez, Harindra D Sathkumara, Ana Maria Valencia-Hernandez, Saparna Pai, Andreas Kupz — Science advances. Volume 12(34): eaec7792. Aug 21, 2026.
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Created 22 Aug 2026

High-spatiotemporal resolution deuterium metabolic imaging enables in vivo phenotyping of intra- and intertumoral heterogeneity.

by Xinjie Liu, Sufei Wang, Jinrui Zhao, ShaSha Wang, Peng Sun, Xin Zhou, Maili Liu, Chaoyang Liu, Lucio Frydman, Qingjia Bao — Science advances. Volume 12(34): eaef4377. Aug 21, 2026.
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Created 22 Aug 2026

Enriched experience increases reciprocal synaptic connectivity and coding sparsity in higher-order cortex.

by Rajat Saxena, Justin L Shobe, Aida M Andujo, Wing Ning, Christelle Anaclet, Bruce L McNaughton — Science advances. Volume 12(34): eaec3893. Aug 21, 2026.
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Created 22 Aug 2026

Orthogonal DNA barcoding enables subpopulation-resolved extracellular vesicle miRNA profiling.

by Ye Zhang, Yitong Zhu, Yu Zhang, Shijin Peng, Diheng Wu, Wenbin Li, Tingting Ji, Siting Chen, Yuanhong Lin, Huihong Yang, Yuhang Guo, Bo Li, Chunchen Liu, Bo Situ, Xiaohui Yan, Lei Zheng — Science advances. Volume 12(34): eaef8133. Aug 21, 2026.
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Created 22 Aug 2026

Matrix stress relaxation drives glioblastoma cell response in viscoelastic biomaterials.

by Sadegh Ghorbani, Michelle S Huang, Daiyao Zhang, Yueming Liu, Christopher Long, Riley Zwetsloot, Esther A T Mozipo, Rameshwar R Rao, Annika Enejder, Sarah C Heilshorn — Science advances. Volume 12(34): eaef7087. Aug 21, 2026.
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Created 22 Aug 2026

δ2-Protocadherins organize parallel indirect basal ganglia circuits.

by Naosuke Hoshina, Joshua M Boeckers, Erin M Johnson-Venkatesh, Miyuki Hoshina, Kana Matsumoto, Abhijnana Das, Veronica R Rally, Jaanvi Sant, Akiko Terauchi, Shinji Kinoshita, Takafumi Inoue, Hisashi Umemori — Science advances. Volume 12(34): eaec8746. Aug 21, 2026.
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Created 22 Aug 2026

Metabolic-epigenetic rewiring of CCR5^hi monocytes sustains long-term trained immunity against lethal sepsis.

by Lingqi Xu, Wenyan Hao, Yingyi Yang, Yu Wang, Yaoshuang Li, Yuan Gong, Yifang Ding, Jie Huang, Zhenjiang Bai, Qiang Shan, Rui Kang, Jiang Huai Wang, Haichao Wang, Timothy R Billiar, Jian Wang, Daolin Tang, Huiting Zhou — Science advances. Volume 12(34): eaee1634. Aug 21, 2026.
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Created 22 Aug 2026

Geneformer-guided multiomics integration identifies Pbx1 as a network hub of hematopoietic stem cell aging.

by Hiroshi Kobayashi, Shintaro Watanuki, Yusuke Shiozawa, Motohiko Oshima, Shuhei Koide, Naoya Takayama, Takayuki Morikawa, Miho Haraguchi, Shinpei Tamaki, Takayoshi Asakura, Toshio Miyata, Atsushi Iwama, Seishi Ogawa, Keiyo Takubo — Science advances. Volume 12(34): eaeb1346. Aug 21, 2026.
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