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Created 31 Oct 2026
Protocol for a multicenter prospective phase II trial of adjuvant tislelizumab combined with S-1 in subjects with residual primary lesions and node-negative esophageal squamous cell carcinoma (PPIO-008).
by Ying-Jian Wang, Xv Chen, Xian-Feng Xie, Chang-Feng Li, Tao Bao, Xian-Dong He, Kun-Kun Li, Xiang-Shu Pu, Yan He, Wei Guo — Future oncology (London, England). Pages 1-10. Oct 30, 2026.
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Created 31 Oct 2026
Multiscale Brownian dynamics simulations reveal effects of macromolecular crowding on protein-ligand association.
by Riccardo Beccaria, Abraham Muñiz-Chicharro, Rebecca C Wade — Proceedings of the National Academy of Sciences of the United States of America. Volume 123(44): e2617950123. Nov 03, 2026.
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Created 31 Oct 2026
Deep mutational scanning of the GPCR rhodopsin reveals pleiotropic mutational effects and their roles in modulating receptor signaling.
by Steven K Chen, Jing Liu, Belinda S W Chang — Proceedings of the National Academy of Sciences of the United States of America. Volume 123(44): e2624087123. Nov 03, 2026.
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Created 31 Oct 2026
Reply to Yu and Yu: Clarifying the role of carnitine metabolism in the ALDH9A1-associated immunotherapy resistance program.
by Hailei Du, Tong Lang, Xiaoxue Zha, Chao Qu, Ling Chen, Shihua Yao, Xing Feng, Zhaohui Jin — Proceedings of the National Academy of Sciences of the United States of America. Volume 123(46): e2632549123. Nov 17, 2026.
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Created 31 Oct 2026
Guardians of the blood: How Kupffer cells control systemic infection.
by Lindsey Orthner, Josefien W Hommes, Bas G J Surewaard — PLoS pathogens. Volume 22(10): e1014744. Epub Oct 30, 2026.
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Created 31 Oct 2026
Glutamate receptor composition at Drosophila neuromuscular junctions depends on developmental stage and muscle identity.
by Anne Sustar, Chengjie Qiu, Yu Xiong, Dion K Dickman, John C Tuthill — eLife. Volume 15. Oct 30, 2026.
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Created 31 Oct 2026
SR-A1 cooperates with TLR4-NF-κB signaling to drive macrophage TGF-β1 expression and Treg induction during schistosome infection.
by Junyao Shen, Ziling Wang, Chuanhong Huang, Weijie Xue, Yu Wu, Tianyu Fan, Yuanyuan Miao, Chenxu Mao, Jiaojiao Yu, Yalin Li, Lei Xu, Jifeng Zhu, Xiaojun Chen, Yang Dai, Zhigang Lei, Sha Zhou, Chuan Su — PLoS pathogens. Volume 22(10): e1014732. Oct 30, 2026.
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Created 31 Oct 2026
kri-1/KRIT1 promotes innate immune and lipid homeostasis in the C. elegans intestine.
by Akshay Alaghatta, Samantha Y Tse-Kang, Daniel Bollen, Khursheed A Wani, Nicholas D Peterson, Read Pukkila-Worley — PLoS genetics. Volume 22(10): e1012166. Oct 30, 2026.
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Created 31 Oct 2026
GPR183 senses 7α,25-OHC to drive Treg differentiation and tumor immune evasion via AXL-JAK2-STAT5 signaling.
by Yang Qu, Yihan Xu, Jingchao Bai, Yuhan Zhang, Ning Ji, Xinxin Li, Hui Li — Science advances. Volume 12(44): eaeh9736. Oct 30, 2026.
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Created 31 Oct 2026
Integrative discovery and functional dependency mapping uncover essential chimeric RNAs in the active transcriptome.
by Samir Lalani, Samuel Haddox, Kendall Bromley, Shafaque Zahra, Marina Wang, Mason Ingram, Sehajroop Gadh, Shriya Gunalan, Sulun Ke, Qiong Wang, Fujun Qin, Eric Hendrickson, Anja Bielinsky, Hui Li — Science advances. Volume 12(44): eaei0901. Oct 30, 2026.
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