Latest Research Publications - Life Science Network

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Created 06 Nov 2026

PADL1NK-005 study design: a phase III trial of fetrastobart vedotin (Fetra-V) vs docetaxel in patients with previously treated tumor PD-L1-positive NSCLC.

by Mehmet Altan, Vishal Navani, Hye Ryun Kim, Longhua Sun, Luis Paz-Ares, Izabela Chmielewska, Chien-Chung Lin, Kristof Cuppens, Ioannis Mountzios, Nir Peled, Federico Cappuzzo, Bo Wang, Caicun Zhou, Nicolas Girard, Yijia Wang, Sandra T Asanin, Mo Huang, Edward Garon — Future oncology (London, England). Pages 1-12. Nov 06, 2026.
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Created 06 Nov 2026

Treatment outcomes of tucatinib in combination with trastuzumab and pertuzumab as a maintenance therapy for people with HER2+ metastatic breast cancer: a plain language summary of findings from HER2CLIMB-05.

by Veronique Dieras, Giuseppe Curigliano, Miguel Martin, Florence Lerebours, Junji Tsurutani, Marie-France Savard, Katarzyna J Jerzak, Xichun Hu, Luciana Carla Martins de Aquino Pimentel, Ciara C O'Sullivan, Eriko Tokunaga, Alicia Okines, Chiun-Sheng Huang, William Jacot, Joohyuk Sohn, Eduardo Cronemberger Silva, Volkmar Muelle, Shan Yang, Giovanna Granata, Qi Shen, Erika Hamilton — Future oncology (London, England). Pages 1-10. Nov 06, 2026.
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Created 06 Nov 2026

Additional Somatic KIT Mutations in a Family Carrying the Germline K558N Variant: Evidence Consistent With a Multistep Model of Tumor Development.

by Katja Maurus, Armin Wiegering, Andreas Rosenwald, Elena Gerhard-Hartmann, Michael Meir — Genes, chromosomes & cancer. Volume 65(11).
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Created 06 Nov 2026

Complex and Cryptic KMT2A::MLLT10 Rearrangements in Acute Myeloid Leukemia Resolved by Optical Genome Mapping.

by Fatma AlBulushi, Nicolas Salcedo-Porras, Julia N C Parlow, Christine Nast, Zeid Hamadeh, Dan Li, Tara Spence, Eric McGinnis — Genes, chromosomes & cancer. Volume 65(11).
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Created 06 Nov 2026

H. pylori induces ferroptosis and inhibits malignant progression of gastric epithelial cells via STAT1/SLC7A11 axis.

by Tingting Huang, Guoling Meng, Xichen Yu, Yiran Yao, Yiyue Li, Qinrong Wang, Liya Bao, Ying Liu, Wei Hong, Yan Zhao, Yuan Xie — Microbiology spectrum. Pages e0222126. Nov 06, 2026.
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Created 06 Nov 2026

NRF2 and mutant p53 separately regulate redox balance in esophageal squamous cell carcinoma through metabolic reprogramming.

by Guodong Deng, Yue Liu, Wei Zheng, Lili Qiao, Lei Xu, Yanan Yang, Hui Yuan, Xiaohong Yu, Wei Jiang, Xiying Yu — Cancer biology & therapy. Volume 27(1): 2745287. Dec 31, 2026.
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Created 06 Nov 2026

Quaternary structure and activity of glutamate dehydrogenase are regulated by reversible S-palmitoylation and mitochondrial acyl-protein thioesterases.

by Michael Salsaa, Huu Tram Anh Huynh, Charneal L Dixon, Jonathan St-Germain, Haggag S Zein, Ella M Potvin, David N Langelaan, Brian Raught, Gregory D Fairn — Protein science : a publication of the Protein Society. Volume 35(12).
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Created 06 Nov 2026

Survival in adjuvant immunotherapy: Distinct estimands and methodological trade-offs.

by Marie B Weitemeyer, Marco Donia, Lisbet R Hölmich, Eva Ellebaek — Journal of the European Academy of Dermatology and Venereology : JEADV. Nov 06, 2026.
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Created 06 Nov 2026

Knowledge-Belief-Action Theory-Guided Nursing and Postoperative Recovery, Nutritional Status, and Quality of Life After Radical Esophagectomy: A Retrospective Comparative Study.

by Wen Du, Ting Ren, Zhenzhen Xia — Journal of visualized experiments : JoVE. Issue 237. Nov 05, 2026.
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Created 06 Nov 2026

Syndrome-Element Network Reorganization Across Gastric Precancerous Lesion Stages: A Simulation-Validated Analysis Pipeline.

by Xuanye Li, Tian Xia, Zhuohao Li, Shaoli Wang, Zhen Liu — Journal of visualized experiments : JoVE. Issue 237. Nov 05, 2026.
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