Latest Research Publications - Life Science Network

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Created 10 Sep 2026

Exposure-Response Analysis of Enfortumab Vedotin Plus Pembrolizumab as First-Line Therapy for Locally Advanced or Metastatic Urothelial Cancer.

by Vaishali L Chudasama, Helen Kastrissios, Hossam Kadry, Daping Zhang, Salaheldin Hamed, Srinivasu Poondru, Souvik Bhattacharya, Russ Wada, Amit Garg, Yen Lin Chia — Clinical pharmacology and therapeutics. Sep 09, 2026.
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Created 10 Sep 2026

Intravenous gene therapy improves life span and clinical outcomes in a feline model of Sandhoff disease.

by Anne S Maguire, Nathan L Ta, Amanda L Gross, Courtney J Garrett, Arthur D Zimmerman, Elise B Diffie, Devin E Osterhoudt, Sara H Pacer, Morgan L Mitchell, Jessica S Cannon, Paige I Hall, Maninder Sandey, Robert C Cole, Thomas N Seyfried, Heather L Gray-Edwards, Miguel Sena-Esteves, Douglas R Martin — Science translational medicine. Volume 18(866): eadx2447. Sep 09, 2026.
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Created 12 Sep 2026

Malic enzyme 1 senses L-lactate to determine tumor heterogeneity.

by Si-Yi Cao, Kewen Hu, Shijing Huang, Xiao-Lin Guan, Jian Wang, Yuan Shen, Hui Ming, Aihong Gu, Chao Wang, Xiao Shen, Qing Wu, Zhengjun Chen, Miao Yin, Wenyu Wen, Qun-Ying Lei — Signal transduction and targeted therapy. Volume 11(1). Sep 11, 2026.
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Created 12 Sep 2026

Persistent Food Insecurity Inequities by age, gender, race/ethnicity, and educational attainment among US Adults with and without Symptoms of Anxiety and Depression: Using Intersectional Multilevel Analysis of Individual Heterogeneity and Discriminatory Accuracy (I-MAIHDA).

by McKaylee Robertson, Jenna Sanborn, Angela Parcesepe, Kate Penrose, Sasha Fleary, Denis Nash, Luisa N Borrell — Annals of epidemiology. Pages 110274. Sep 11, 2026.
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Created 10 Sep 2026

Early vs Delayed Steroid Treatment in Cerebral Amyloid Angiopathy-Related Inflammation: A Retrospective Cohort Study.

by Giulia Negro, Michele Rossi, Elisa Cavarsaschi, Giorgia Orsani, Benedetta Storti, Mattia Losa, Nicolò Dell'Orto, Elena Moscatelli, Alessandro Francia, Giulia Marinoni, Andrea Donniaquio, Massimo Del Sette, Matteo Pardini, Anna Bersano, Jacopo C DiFrancesco — Neurology(R) neuroimmunology & neuroinflammation. Volume 13(6): e200639. Epub Sep 09, 2026.
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Created 10 Sep 2026

Food-based enteral formulas in pediatric clinical practice: an expert opinion.

by Graeme O'Connor, Antonella Diamanti, Chiara Maria Trovato, Claudio Romano, Gerard J Minor, Guy Letellier, Koen Huysentruyt, Lisa M Epp, Randi Tobberup, Sarah Durnan, Valeria Dipasquale, Valerie Marchand, Frederic Gottrand — Expert review of gastroenterology & hepatology. Sep 10, 2026.
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Created 12 Sep 2026

Functional alignment robotic-assisted TKA improves clinical outcomes compared with conventional mechanical alignment TKA: A single-surgeon randomised controlled non-inferiority trial with 2-year follow-up.

by Remco Coenen, Arne Peeters, Peter Bollars, Dinesh Nathwani, Ali Albelooshi, Max Til Ettinger, Arnaud Deltour, Martijn Gerhardus Maria Schotanus — Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA. Sep 11, 2026.
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Created 09 Sep 2026

Human and mouse adrenal glands are characterized by species-specific steroidogenic states and tissue turnover.

by Maria E Kastriti, Denis Maksimov, Julia Krupinova, Marina Utkina, Dmitry Beltsevich, Anna Roslyakova, Olga Glazova, Samira Kaziakhmedova, Alina Ryabova, Anna Kuznetsova, Anastasia Shcherbakova, Ekaterina Bondarenko, Zoia Antysheva, Eugene Albert, Lilia Urusova, Anastasia Lapshina, Anastassia Chevais, Ekaterina Avsievich, Valentin Trofimov, Galina Melnichenko, Natalya Mokrysheva, Ivan Dedov, Lukas Englmaier, Julian Petersen, Oleg Gusev, Andreas Heinzel, Rainer Oberbauer, Pavel Volchkov, Peter V Kharchenko, Igor Adameyko — Nature genetics. Volume 58(9): 2270-2283. Epub Sep 08, 2026.
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Created 10 Sep 2026

Two banks of the same river: a conversation with Dr Justice D Y Chandrachud, the fiftieth Chief Justice of India, on medical humanities and jurisprudence.

by Satendra Singh, Gayathri Prabhu — Medical humanities. Sep 09, 2026.
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Created 09 Sep 2026

Kinematic Alignment in TKA Using the Contralateral Healthy Knee as Reference: A Combined Finite Element and Clinical Analysis.

by Lingce Kong, Wei Lin, Huijun Kang, Muchen Yu, Ming Li, Chenyue Xu, Fei Wang — Orthopaedic surgery. Sep 08, 2026.
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