Latest Research Publications - Life Science Network

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Created 12 Nov 2026

A viral replication level-dependent continuum of transcriptional and microRNA reprogramming in HIV-1-infected microglia links productive infection to neurocognitive-associated gene networks.

by Zahra Vahdat, Suman Sharma, Khanghy Truong, Amrit Koirala, Sakuni Rankothgedera, Shiyanth Thevasagayampillai, Aaranyah Kandasamy, Sandra L Grimm, Shuntai Zhou, Preethi H Gunaratne, Jason T Kimata, Consuelo Walss-Bass, Cristian Coarfa, Andrew P Rice — mBio. Pages e0236526. Nov 12, 2026.
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Created 12 Nov 2026

Bone metastases identify a high-risk subgroup in metastatic neuroendocrine tumors with particular relevance in NETs of unknown primary.

by Annie Mathew, Anna Kyewski, Pia Hauptmeier, David Kersting, Benedikt M Schaarschmidt, Dagmar Fuhrer, Harald Lahner — Frontiers in endocrinology. Volume 17: 1906789. Epub Oct 28, 2026.
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Created 12 Nov 2026

The role of high-resolution manometry in the assessment of altered foregut anatomy: scoping review and interpretation recommendations.

by Alberto Barchi, C Prakash Gyawali, John Pandolfino, Gwen M C Masclee, Niek Warringa, Edoardo Vespa, Edoardo V Savarino, Renato Salvador, Sabine Roman, Dustin A Carlson, Rena Yadlapati, Albert J Bredenoord — The American journal of gastroenterology. Nov 12, 2026.
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Created 12 Nov 2026

Discovery of Novel Orally Bioavailable STING Inhibitors with 4,5,6,7-Tetrahydropyrazolo[1,5-a]pyrazine Moiety for STING-Mediated Inflammatory Disorders.

by Guangcai Ma, Ruikun Peng, Chaoxin Wang, Jiawen Xu, Xi Han, Jiaqian Zhang, Yufei Lu, Suyang Sun, Qi Liu, Huajian Tang, Weilei Jiang, Jielin Wan, Zhiqi Feng, Liu Liu, Qinglong Xu, Haoliang Yuan, Xiaoan Wen, Hongbin Sun, Liang Dai — Journal of medicinal chemistry. Volume 69(21): 26314-26335. Nov 12, 2026.
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Created 12 Nov 2026

Salinity acclimation induces hepatic immune-redox remodeling and intestinal mucosal adaptation in Nile tilapia: insights from multi-tissue transcriptomics and gut microbiota profiling.

by Ya-Xin Wang, Pichayapa Meekuan, Zhuo-Hang Feng, Shuang-Yue Luo, Zhao Li, Zheng-Xiang Zhang, Noratat Prachom, Xueweijie Chen, Zhi-Shuai Hou — Fish physiology and biochemistry. Volume 52(6). Nov 11, 2026.
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Created 13 Nov 2026

The rise of agentic AI in drug discovery from static tools to autonomous virtual scientists.

by Donghai Zhao, Meijing Fang, Lexiao Mao, Yuchen Zhu, Qun Su, Hui Shi, Hongxia Xu, Lanqing Li, Tingjun Hou, Chang-Yu Hsieh — npj drug discovery. Volume 3(1). Oct 12, 2026.
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Created 13 Nov 2026

Risk factors and bacterial epidemiology of recurrent bloodstream infections-a population-based cohort study.

by Ylva Mattisson, Tuong Tang, Safaa Raja, Julia Sadrian, Torgny Sunnerhagen, Gustav Torisson, Oskar Ljungquist — Infection. Nov 12, 2026.
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Created 12 Nov 2026

Diagnostic Accuracy and Procedural Efficiency of ACR TI-RADS, EU-TIRADS, and K-TIRADS in ≤ 10 mm Thyroid Nodules Using Bethesda Cytology: A Cohort of 998 Nodules.

by Mustafa Bilgili, Sinan Karatoprak, Oğuz Aslan, Gamze Türk, Ebru Akay — The British journal of radiology. Nov 12, 2026.
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Created 13 Nov 2026

Nodulation Signaling Pathway 2: A Proposed Multifunctional Signaling Hub for Coordinating Plant Architecture, Rhizosphere Chemistry, and Symbiotic Associations Under Nutrient Stress.

by Yanting Wang, Yanni Zhao, Ranran Liu, Shulei Wang, Yuanfeng Li — Biology. Volume 15(19). Sep 22, 2026.
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Created 13 Nov 2026

A Multicyclic Catalytic Network Enabling ROS Amplification, Metabolic Disruption, and Immune Modulation for Antitumor-Antibacterial Therapy.

by Chao Ban, Hailing Lin, Mingxin Cheng, Shuanglong Chen, Ziteng Hao, Yun Shen, Yubin Sha, Yangyin Xue, Jinkang Feng, Jiaxuan Chen, Weiwei Guo, Wancai Que — ACS applied materials & interfaces. Nov 12, 2026.
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