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Prefrontal to ventral tegmental area dynamics drive contingency degradation

Journal content Created on 06 May 2026 Nature

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Nature, Nature Publishing Group

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Nature, Published online: 06 May 2026; doi:10.1038/s41586-026-10443-5

This work provides a mechanistic understanding of how certain prefrontal circuits in the rodent brain permit flexibility to selectively stop learned behaviours through interactions with core subcortical reward systems.

Garret D. Stuber

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