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Deprotonation and Alkylation of Weakly Acidic C(sp3)─H Bonds Through In Situ Generation of a Strong Hydride Base From 1,1,3,3‐Tetramethyldisiloxane and Potassium tert‐Butoxide

Journal content Created on 24 Aug 2026 Angewandte Chemie Int Ed

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Angewandte Chemie Int Ed, Wiley-VCH

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Deprotonation and Alkylation of Weakly Acidic C(sp3)─H Bonds Through In Situ Generation of a Strong Hydride Base From 1,1,3,3‐Tetramethyldisiloxane and Potassium tert‐Butoxide

Piers St. Onge, Brandon White, Han Yao, Travis Dudding, Stephen G. Newman

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