[Articles] Safety and lipoprotein(a)-lowering effects of Kylo-11, a non-canonical, long-duration small interfering RNA targeting lipoprotein(a): a first-in-human, randomised, double-blind, placebo-controlled, phase 1 trial

Journal content Created on 28 Aug 2026 The Lancet

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The Lancet, The Lancet (Reed Elsevier)

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Ashish Sarraju, Xiaolin Du, Luping Zhou, Luke J Laffin, Kathy Wolski, Yumei Gu, Ziyang Liu, Qinsheng Zhang, Kunyuan Cui, Xiaolan Yong, Steven E Nissen

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