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Hybridization‐Mediated Reversible sgRNA Caging Enables Tumor‐Selective Gene Editing for Potentiating Antitumor Immunity via cGAS Demethylation

Journal content Created on 14 Oct 2026 Angewandte Chemie Int Ed

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Angewandte Chemie Int Ed, Wiley-VCH

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Hybridization‐Mediated Reversible sgRNA Caging Enables Tumor‐Selective Gene Editing for Potentiating Antitumor Immunity via cGAS Demethylation

Haoyu Zhang, Yajie Li, Yehan Wang, Ziyin Zhao, He Yang, Jiawen Hu, Desheng Cao, Guanglin Wang, Ran Zhu, Xun Liu, Lichen Yin

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