Speaker
Sara Bursomanno, Marie-Louise Lunn
When and where
Starts: Wednesday, 19 March 2025
Ends: Wednesday, 19 March 2025
Location:
Xtalks, Toronto, Canada
Location details: Free Registration on Xtalks.com
Event description
The use of animal-free reagents in the upstream manufacturing of biologic drugs is a common standard in biomanufacturing, essential for enhancing consistency and safety.
Insulin has emerged as a key component in cell culture for biomanufacturing, improving a wide array of processes such as monoclonal antibody (mAb) production in CHO cells, virus production in various cell types, stem cell culture performance and production of viral vectors for gene therapy.
Another crucial element in cell-based vaccine production is trypsin, which is essential for virus expansion and activation of specific virus particles, notably in the case of influenza. However, the use of animal-derived trypsin carries the inherent risk of introducing adventitious contaminants, potentially leading to cell culture infection with serious consequences for both patients and production continuity.
The introduction of the enzyme TrypsiNNex® effectively addresses these safety and consistency concerns. As a high-purity, recombinantly produced, animal-free trypsin, the enzyme ensures a more robust production process, effectively reducing the risk of contamination.
Through a controlled production process, the enzyme maintains an inactive form until stabilization, which results in a high and consistent proportion of β-trypsin and makes it an ideal choice for virus-vaccine production, resulting in cost savings and improved efficiency.
In this webinar, the expert speakers will illustrate how both insulin and TrypsiNNex® significantly enhance the safety and efficiency of upstream biomanufacturing processes, thereby enhancing the overall efficiency of therapeutic biologics production. Furthermore, they will delve into how the implementation of reagents such as insulin plays a significant role in reducing overall upstream costs by increasing process efficiency.
Register for this webinar today to explore how innovative animal-free reagents are transforming upstream biomanufacturing.
Further details
IMPORTANT: In order to register to this free webinar you must register directly on Xtalks via the following URL: https://xtalks.com/webinars/enhancing-efficiency-and-safety-in-upstream-biomanufacturing/
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