Employer
Hochschule Bremen, Bremen, Germany
Description
We offer a PhD position in the interdisciplinary DFG-funded project "Bio-inspired multizonal protein scaffolds as novel cartilage model system".
Due to increasing life expectancy, many patients in our ageing population suffer from cartilage defects. This requires new strategies in cartilage tissue engineering. Therefore, the aim of this project is to develop multizonal protein scaffolds from collagen and fibrinogen nanofibers and to combine them with polysaccharide hydrogels to support chondrogenic differentiation of mesenchymal stem cells.
Your tasks:
Fabrication of nanofibrous protein scaffolds by self-assembly and analysis of the scaffold topography with scanning electron microscopy
Mechanical characterisation of the composite scaffolds and characterisation of the swelling behavior
Spectroscopic analysis of the protein conformation.
Further information on this DFG-funded project are available here: https://gepris.dfg.de/gepris/projekt/542992440?language=en
More information on our research: http://www.hs-bremen.de/biophysics
Candidate requirements
YOUR PROFILE
- A successfully completed Masters degree in biomaterials science, biochemistry, biophysics, biology or related areas
- Good expertise in protein biochemistry and / or biofabrication processes
- Profound experience in developing experimental techniques for interdisciplinary research in biomaterials science
- Experience in secondary structure analysis of proteins, e.g. FTIR and circular dichroism spectroscopy
- Very good language skills in English (at least level B2)
- Good knowledge of computer-based data analysis (e.g. Origin, R, statistics software)
- Willingness to work in interdisciplinary teams
- Experience in writing scientific publications
Desirable are:
- Very good language skills German (at least level B2)
- Experience in imaging techniques, e.g. scanning electron microscopy and fluorescence microscopy
- Experience in fabrication and characterization of protein nanofibers
Further details
Possible start of employment: Tuesday, 01 April 2025.
Contract: Part-time, Fixed-term
Please mention Life Science Network when applying
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