Plasmid-encoded anatoxin biosynthesis in benthic cyanobacteria

Authors

Gibis, F. M., Rieth, D., Geist, J., Schoenle, A., Bauer, F., Schampera, C., Waldvogel, A.-M.

Abstract

Anatoxin-producing cyanobacteria pose growing ecological and public health risks, yet the genomic organization of anatoxin biosynthesis remains poorly resolved. Using complete genome assembly of a benthic cyanobacterium of the genus Microcoleus, we show that the entire anatoxin biosynthetic gene cluster is encoded on a small circular plasmid rather than the chromosome. This unexpected localization suggests enhanced mobility of anatoxin biosynthesis and has implications for toxin evolution, release, and environmental surveillance.

Preprint server: bioRxiv
The authors list and abstract were imported from bioRxiv on 27 Jun 2026.

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