golgi: open-source software for automated nerve model generation and recruitment simulation

Authors

Lung, D., Jia, Y., Moro, A., Fachino, M., Haberbusch, M.

Abstract

golgi is an open-source platform that takes a peripheral nerve from image to stimulated fiber population through a single graphical interface, with an equivalent scriptable Python API and command-line interface for batch and high-performance use. It integrates promptable image segmentation, automated multi-region tetrahedral meshing, anisotropic finite-element solution of the extracellular field with an explicit perineurium contact impedance, generation of realistic fiber populations and their three-dimensional trajectories, and biophysical activation thresholds through interchangeable backends--NEURON (via PyFibers) and a GPU-accelerated surrogate (AxonML). Every study exports as an integrity-hashed bundle whose image-to-recruitment provenance is verifiable byte-for-byte. golgi lowers the barrier to in-silico peripheral nerve stimulation modeling for experimentalists and clinicians, using a fully open finite-element stack with no commercial dependencies.

Preprint server: bioRxiv
The authors list and abstract were imported from bioRxiv on 14 Jul 2026.

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