Early-life stress-induced gut dysbiosis is ameliorated by nicotinamide treatment

Authors

Srivastav, S., Chaudhari, P. R., Suryavanshi, S., Pange, N., Vaidya, V. A., Anand, A.

Abstract

Early life stress (ELS) in the form of adverse experiences in childhood results in multiple psycho-physiological pathologies during adulthood and accelerates aging. Such pathologies are recently observed to be alleviated upon nicotinamide treatment in a maternal separation model of ELS. We report a nicotinamide-driven amelioration of gut dysbiosis in middle-aged rodents with a history of neonatal maternal separation.

Preprint server: bioRxiv
The authors list and abstract were imported from bioRxiv on 21 Aug 2026.

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