Latest Research Preprints - Life Science Network

Heads up!

This list contains preprints from the last 30 days only. Use the search function to access older preprints.

The default sorting of preprints in this list is by the date when the preprint was uploaded or imported to our database (shown on top). Publication date is indicated below the title.

Created 23 Aug 2026

RERE and the Mediator complex cooperate with EWSR1::FLI1 in the reprogramming of Translation and Alternative Splicing, the latter being a therapeutically targetable vulnerability in Ewing sarcoma

by Cuervas, I., Bonnal, S., Andrades, E., Mateo-Lozano, S., Sanchez-Jimenez, M., Berenguer-Molins, P., Acedo-Terrrades, A., Bodalo-Torruella, M., Perera-Bel, J., Gimeno, R., Roldan, M., Prada, E., Valcarcel, J., Mora, J., Hernandez-Munoz, I.
- Views 11
- More stats
- - Report or request
Created 23 Aug 2026

Urothelial-lineage master transcription factor hub proteomics shows mechanisms impeding urothelial cancer cell differentiation

by Schuerger, C., Biswas, S., Ng, K. P., Cardone, L., Gu, X., Ganguly, S., Tohme, R., Durmaz, A., Stich, M., Lindner, D. J., Jha, B., Mian, O. Y., Saunthararajah, Y.
- Views 12
- More stats
- - Report or request
Created 23 Aug 2026

Radiological Patterns in Maxillofacial Ewing Sarcoma: A systematic review with pooled patient-level descriptive analysis

by George, A. B., Maharana, S., Agarwal, R., George, A. M., Khurana, S.
- Views 8
- More stats
- - Report or request
Created 23 Aug 2026

A multilayered in silico analysis links UHRF1, DNA methylation and developmental chromatin memory to lineage-dependent prognosis in gastric, renal and adrenal cancers
- Views 11
- More stats
- - Report or request
Created 23 Aug 2026

BET BD2 inhibition facilitates SPOP-mediated degradation of chromatin-associated BRD4/BRD4-NUT, a therapeutic vulnerability in NUT carcinoma
- Views 24
- More stats
- - Report or request
Created 23 Aug 2026

Context-dependent variant interpretation from Mendelian disease to genetic predisposition: a proof-of-concept using LPL

by Yang, Q., Zou, W.-B., Pu, N., Li, Y., Hu, Y., Wang, Y.-C., Liu, X., Genin, E., Masson, E., Wang, J., Ferec, C., Cooper, D. N., Li, W., Chen, J.-M.
- Views 16
- More stats
- - Report or request
Created 23 Aug 2026

Functional evaluation of a natural AAV capsid liver targeting motif in human hepatocytes

by Unzu, C., Chen, A. X., Mancio-Silva, L., Zinn, E., Wen, Y., Llinares, C., LLanos, A., Zhu, C., Fieldsend, A., Sanmiguel, J., Bissig-Choisat, B., Bissig, K.-D., Alexander, I., Bhatia, S., Vandenberghe, L. H.
- Views 33
- More stats
- - Report or request
Created 23 Aug 2026

reserBUGS: A reservoir computing framework for probabilistic forecasting of ecological abundance time series

by Mohedano-Munoz, M. A., Galeano, J., Pastor, J. M., de Aledo, J. G., Bartomeus, I., Allen-Perkins, A.
- Views 21
- More stats
- - Report or request
Created 23 Aug 2026

LSm4 biomolecular condensates drive XRN2-mediated RNA decay at DNA double-strand breaks to facilitate repair

by Darawshe, M. M., Bishara, L. A., Abu-Zhayia, E. R., Barisaac, A. S., Machour, F. E., Elmor, C., Ayoub, N.
- Views 11
- More stats
- - Report or request
Created 23 Aug 2026

Method Choice, Not Biology, Determines In Silico Perturbation Results: A Systematic Evaluation of Eight Methods Across Four Datasets

by Wenjie, G., Wu, S., Hu, G., Yang, Z., Wang, Z., Cai, J., Mao, J.
- Views 17
- More stats
- - Report or request