Preprints

Created 11 Jul 2026

Functions of TIAM1 at the interface of centriole assembly and autolysosome cycling

by Coelho, P. A., Yu, C., Glover, D. M.

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Created 11 Jul 2026

Dichloroacetate improves animal survival, growth, neuromuscular activity, mitochondrial stress and physiology, and elevated lactate in C. elegans pdha-1 and dld-1 RNAi models of pyruvate dehydrogenase complex deficiency (PDCD)

by Remes, C., Mathew, N. D., Miranda, V., Haroon, S., O'Hara, T., Anderson, V. E., Lavorato, M., Keith, K., Xiao, R., Nakamaru-Ogiso, E., Falk, M. J.

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Created 11 Jul 2026

Cell-type-specific ATF6α programs regulate epithelial mitochondrial homeostasis and pericyte remodeling during physiological and exposure-accelerated lung aging

by Huang, X., Bard, J. E., Tumenbayar, B.-I., Vedagiri, K., Nelson, C. E., Kenche, H., Reynolds, C. E., Leme, A. S., Moore, S. J., Perry, N. A., Shapiro, S. D., Perry, Y., Bae, Y., Blumental-Perry, A.

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Created 11 Jul 2026

Acidosis-triggered fatty acid overload induces endothelial cell dysfunction.

by Al-Siyabi, S., Ibanez, S., Serafimov, K., Lallement, J., Marchand, D., Laloux, F., Guilbaud, C., Demulder, D., Vlieghe, H., Moghassemi, S., Bouzin, C., Amorim, C., FERON, O., Dessy, C.

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Created 11 Jul 2026

Volatile diacetyl triggers rapid fmo-2 expression through DHAP-glycerol shunt induction

by Giorda, M., Sen, A., Denzel, M. S.

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Created 11 Jul 2026

Gene Supplementation of MYO7A or activation of Myo7b for treatment of Usher syndrome 1B

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Created 11 Jul 2026

Domain Insertion Improves the Precision of a CRISPR Adenine Base Editor

by Müller, M. M., Southern, N. T., Niopek, D.

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Created 11 Jul 2026

Transmembrane aminopeptidase Q (Taqpep) is a common mechanism in the establishment of periodic patterning in skin and intestine

by Dershowitz, L. B., McGowan, K. A., Liu, Z., Brady, B. M., Druckmann, S., Marklund, U., Barsh, G. S., Kaltschmidt, J. A.

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Created 11 Jul 2026

Organ-resolved endothelial regulatory programs link aging and metabolic overload to vascular immune remodeling

by Yokoyama, M., Nakayama, A., Taki, Y., Chen, M., Gong, Y., Shiina, M., Kono, T., Fujimoto, M., Ito, K., Ikeda, J.-i., Tanaka, T.

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Created 11 Jul 2026

Dynein-microtubule forces drive nucleokinesis and transmigration in T cells

by Tagay, Y., Zhovmer, A. S., Sarkar, N., Stoop, J., Su, L., Flezsar, L., Peterman, E., Rasmussen, J. P., Cartagena-Rivera, A. X., Tsygankov, D., Tabdanov, E. D.

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