Latest Research Preprints - Life Science Network

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This list contains preprints from the last 30 days only. Use the search function to access older preprints.

The default sorting of preprints in this list is by the date when the preprint was uploaded or imported to our database (shown on top). Publication date is indicated below the title.

Created 12 Sep 2026

ATAC-seq and MNase-seq Detect Distinct Modes of Chromatin Accessibility

by Stoeber, S. D., Godin, M., Bai, L. D.
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Created 24 Sep 2026

Leakage-controlled benchmarking reveals generalization limits of deep learning for protein-ligand binding affinity prediction

by Wang, L., Cheng, J.
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Created 20 Sep 2026

An RNase Toxin Hijacks Elongation Factor-Tu to Cleave the Ribosomal Sarcin-Ricin Loop

by Hespanhol, J. T., Blackburn, T. M., Pham, K., Varshney, A., Nicastro, G. G., de Souza, R. F., Aravind, L., Johnson, A., Keiler, K. C., Dunham, C. M., Bayer-Santos, E.
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Created 12 Sep 2026

Engineering circular RNA expression systems to minimize contaminating linear RNA byproducts

by Fields, C. J., Fujiwara, R., Wright, B. W., Stringer, B. W., Conn, S. J., Wilusz, J. E.
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Created 19 Sep 2026

p53 knockout drives stage-specific long non-coding RNA reprogramming during human neural differentiation and glioma organoid tumorigenesis.

by Stasi, F., Manzari, A. R., Siciliano, V., Binda, E., Pazienza, V., Brunetti, V., De Vittorio, M.
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Created 09 Sep 2026

A single-nucleus multiomic and spatial atlas of gene regulation in human spermatogenesis

by Bhaskaran, J., Ing-Simmons, E., Balaguer Balsells, I., Di Persio, S., Chan, M. M., Politz, M., Cremers, J.-F., Rotte, N., Kliesch, S., Friedrich, C., Tuettelmann, F., Ernst, C., Laurentino, S., Neuhaus, N., Vaquerizas, J. M.
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Created 14 Sep 2026

Targeted dephosphorylation of Tau at the endogenous level promotes its association with microtubules.

by Sathe, G., Berterame, F., Cartwright, T., Spallek, R., Zhao, J.-F., Bagale, A. R., Gourlay, R., Wood, N. T., Macartney, T. J., Sapkota, G. P.
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Created 19 Sep 2026

An Artificial Intelligence Model for Longitudinal Assessment of TCR Repertoires in SARS-CoV-2 Vaccine Recipients

by Wang, Z., Zhao, Y., Xiao, X., He, B., Sun, Y., Xiong, S., Qin, C., Zhou, Z., Chang, L., Bai, J., Zhao, W., Liang, W., Yao, J.
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Created 29 Sep 2026

The iron-binding siderophore enterobactin is required for the response of multi-drug resistant Klebsiella pneumoniae to zinc limitation

by Singer, J. R., Doyle, D. A., Kunkle, D. E., Burroughs, O. S., Service, R. J., Chazin, W. J., Skaar, E. P.
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Created 15 Sep 2026

Time-resolved decoding of uncertainty about stimulus features from human EEG

by Nestor, J., Tian, K. J., Chapman, A. F., Denison, R. N.
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