Preprints

Created 15 Sep 2026

Discrete synaptic states and context-modulated readouts support continual learning

by Gao, Y., Mihalas, S., Turcu, D.

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Created 20 Sep 2026

Sleep spindles stabilize human thalamocortical networks, inhibiting pathological disruptions

by Jaber, K., Ho, A., Ye, H., Bosque-Varela, P., Aiello, G., Avigdor, T., Shenoy, K., Ramani, P., Wadi, L., Thomas, J., Klimes, P., Richardson, R. M., Southwell, D. G., Hadar, P. N., Cash, S. S., Salami, P., Carlson, D., Zelmann, R., Frauscher, B.

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Created 08 Sep 2026

Capsid-specialized protein language models reveal higher-order viral architecture from sequence

by Liu, S., Xia, S., Wang, H.

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Created 25 Sep 2026

Imputing missing counts for waterbird species: A comparison of methods for zero-inflated biodiversity monitoring data

by Bricout, B., Dami, L., Defos du Rau, P., Donnet, S., Galewski, T., Robin, S.

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Created 09 Sep 2026

Synonymous HTT CAA/CCA-loss variants associated with early Huntington disease onset enhance toxicity beyond somatic instability

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Created 18 Sep 2026

Integrating complementary biological information for multi-objective enzyme engineering

by Blalock, N., Sosa, Y., Heuschkel, J., Li, R., Ma, X., Radomkit, S., Wu, H., Buono, F., Song, J., Pefaur, N., Kingsley, L. J., Romero, P. A.

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Created 20 Sep 2026

An RNase Toxin Hijacks Elongation Factor-Tu to Cleave the Ribosomal Sarcin-Ricin Loop

by Hespanhol, J. T., Blackburn, T. M., Pham, K., Varshney, A., Nicastro, G. G., de Souza, R. F., Aravind, L., Johnson, A., Keiler, K. C., Dunham, C. M., Bayer-Santos, E.

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Created 11 Sep 2026

Self-Architecting Protein Transformers: An Empirical Study

by Cirrincione, G., Ficarra, E., Lovino, M.

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Created 17 Sep 2026

Human skin fibrosis with iPSC-derived organoids reveals RUNX2-mediated fibroblast reprogramming

by Khan, J., Mehmood, S., Al Abir, F., Wei, M., Muzaffar, S., Mohiuddin, S., Liu, S., Waseem, M., Akhter, J., Liu, Z., Crossman, D. K., Kamata, M., Chen, J. Y., Raman, C., Elmets, C., Zhang, S., Athar, M., Jin, L.

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Created 20 Sep 2026

Superficial spinal Tac1-lineage neurons are polymodal nociceptive

by Brochoire, L., Larque, P., Zhang, X., Desnoyers, C., Kania, A., Fossat, P., De Koninck, Y., Wang, F.

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