Latest Research Preprints - Life Science Network

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This list contains preprints from the last 30 days only. Use the search function to access older preprints.

The default sorting of preprints in this list is by the date when the preprint was uploaded or imported to our database (shown on top). Publication date is indicated below the title.

Created 17 Sep 2026

Genome-scale perturbation signatures from primary human CD4+ T cells improve genetics-based prioritization of immune drug targets

by Han, A. L., Slotnik, M., Fox, D. A., Dhindsa, R. S., Gudjonsson, J. E., Kahlenberg, J. M., Welch, J.
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Created 20 Sep 2026

A lifespan single-cell atlas of the human developing hippocampus benchmarks familial Alzheimer's disease brain organoids.

by Ivleva, E., Kruikov, E., Arboleda-Velasquez, J. F., Baranov, P.
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Created 04 Sep 2026

Bacterial vitamin sharing emerges from a balance between release and uptake

by Bunbury, F., Janas, T., Mullen, P., Scorza, K., Ghosh, S., Zhang, J., Mani, M., Pfister, C. A., Donnat, C., Kuehn, S.
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Created 30 Sep 2026

Platform-specific count-matrix preprocessing workflows for spatial transcriptomics data analysis

by Du, Y., Li, S., Yang, X., Shu, H., Wang, Z., Zhang, D., Zou, Q., Yuan, Z.
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Created 08 Sep 2026

Capsid-specialized protein language models reveal higher-order viral architecture from sequence

by Liu, S., Xia, S., Wang, H.
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Created 09 Sep 2026

Synonymous HTT CAA/CCA-loss variants associated with early Huntington disease onset enhance toxicity beyond somatic instability
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Created 17 Sep 2026

Neuronal loss reshapes survivor dynamics and limits mechanism inference in excitatory inhibitory neural fields

by Reyes, R. G., Valdes-Sosa, P. A.
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Created 25 Sep 2026

Imputing missing counts for waterbird species: A comparison of methods for zero-inflated biodiversity monitoring data

by Bricout, B., Dami, L., Defos du Rau, P., Donnet, S., Galewski, T., Robin, S.
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Created 05 Sep 2026

Cross-domain confidence reliability and remappability of frozen single-cell representations

by Weng, G., Zhu, D., Zhao, Y., Martin, P. C., Kim, H., Jung, J., Nam, G.-H., Won, K. J.
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Created 20 Sep 2026

Sleep spindles stabilize human thalamocortical networks, inhibiting pathological disruptions

by Jaber, K., Ho, A., Ye, H., Bosque-Varela, P., Aiello, G., Avigdor, T., Shenoy, K., Ramani, P., Wadi, L., Thomas, J., Klimes, P., Richardson, R. M., Southwell, D. G., Hadar, P. N., Cash, S. S., Salami, P., Carlson, D., Zelmann, R., Frauscher, B.
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