Latest Research Preprints - Life Science Network

Preprints

The Preprints module of the Life Science Network is an archive of pre-publication manuscripts. You can use it to upload your own preprints and give your research more exposure. Preprints may also be automatically imported from other databases.

You can upload a preprint here

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This list contains preprints from the last 30 days only. Use the search function to access older preprints.

The default sorting of preprints in this list is by the date when the preprint was uploaded or imported to our database (shown on top). Publication date is indicated below the title.

Created 20 Sep 2026

Identifying Putative Pathogenic Non-Coding Variants in Unresolved Rare Disease Patients Using Topologically Associated Domains

by Gacita, A. M., Pahl, M., Torres, M. D., Ganesan, S., Blair, J. J., Patel, K., Ramakrishnan, R., Conlin, L., Helbig, I., Grant, S. F. A.
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Created 12 Oct 2026

Chain of Structures: Connecting Reasoning and Generation for Protein Design

by Cai, Q., Xu, M., Yan, J., Wang, Z., Liu, Y., Pei, Q., Zhang, Z.
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Created 09 Oct 2026

Exploration of ligand (un)binding trajectories with Rosetta

by Zlobin, A., Eisenhuth, P., Ferrario, V., Meiler, J.
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Created 24 Sep 2026

Generative Access to Make-on-Demand Chemical Space Enables Ultra-Large Virtual Screening

by Zhang, K., Sun, Y., Li, X., Wang, Y., Peng, C., Jin, X., Hu, Q., Huang, J.
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Created 27 Sep 2026

MYC-Hyperactivated Osteosarcoma Models Exhibit Resistance to Cabozantinib plus TIGIT Blockade

by Kappa, S. S., Patel, T., Nirala, B., Kurenbekova, L., Shuck, R., Yustein, J. T.
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Created 22 Sep 2026

Shamonda virus EU1 in Northern Italy, August 2026.
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Created 03 Oct 2026

AbRefine: Framework-Conditioned Refinement for Structure-Guided Antibody CDR Design

by Liu, Q., Xu, X., Cheng, Q., Meng, L., Wu, C., Yang, D., Gao, X., Chen, X.
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Created 19 Sep 2026

Spatially resolved multimodal hallmarks of response to neoadjuvant immunotherapies in the melanoma ecosystem in 2D and 3D
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Created 01 Oct 2026

Chemogenetic Hydrogen Sulfide Rescues Vascular Senescence in Ageing

by Shabanian, K., Shabanian, T., Da Dalt, L., Colucci, M., Eroglu, E., Rodriguez Cetina Biefer, H., Dzemali, O., Hermann, M., Alimonti, A., Norata, G. D., Paneni, F., Ruschitzka, F., Saeedi Saravi, S. S.
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Created 18 Sep 2026

Oncogenic fusions induce an extensive cancer-restricted cryptic proteome in Ewing sarcoma
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