Latest Research Preprints - Life Science Network

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This list contains preprints from the last 30 days only. Use the search function to access older preprints.

The default sorting of preprints in this list is by the date when the preprint was uploaded or imported to our database (shown on top). Publication date is indicated below the title.

Created 29 Sep 2026

EIDD-3525 is a broad-spectrum antiviral against alphavirus infection that targets the nsP4 RNA-dependent RNA polymerase

by Yin, P., Choudhary, S., Wang, S., Davenport, B. J., Truong, P. M., Sticher, Z. M., Krueger, R., Cruz, A. A., Smith, M., Kolykhalov, A. A., Vyshenska, D., Greninger, A. L., Mao, S., Natchus, M. G., Painter, G. R., Merits, A., Kielian, M., Morrison, T. E.
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Created 20 Sep 2026

Identifying Putative Pathogenic Non-Coding Variants in Unresolved Rare Disease Patients Using Topologically Associated Domains

by Gacita, A. M., Pahl, M., Torres, M. D., Ganesan, S., Blair, J. J., Patel, K., Ramakrishnan, R., Conlin, L., Helbig, I., Grant, S. F. A.
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Created 08 Oct 2026

The actin-binding protein drebrin interacts with the respiratory syncytial virus matrix protein and promotes virus particle release.

by Jaouen, T., Marougka, K., Feliciano, M., Jobart-Malfait, A., Sago, L., Bajorek, M., Rameix-Welti, M.-A., Sitterlin, D.
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Created 06 Oct 2026

Streptomyces induces unisexual reproduction of a major human fungal pathogen

by Son, Y.-E., Chen, X., Wright, G., Sun, S., Heitman, J.
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Created 25 Sep 2026

Block of Thalamic 5-HT2A Receptors modulates Tonic GABA-A Inhibition but not Absence Seizures

by Cavaccini, A., Venzi, M., Crunelli, V., Di Giovanni, G.
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Created 20 Sep 2026

Single-Cell Study Designs Are Systematically Underpowered for Small-Effect Genes

by Crampton, C., Fawad, S., Clark, T., Dash, H., Köver, B., Cotton, G., Lee, D., Duff, E., Bottolo, L., Matthews, P. M., Skene, N.
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Created 18 Sep 2026

Interrogation of noncoding schizophrenia risk variants using CRISPR-based functional genomics
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Created 11 Sep 2026

Cyclic-thiourea ionizable lipids program multilamellar mRNA-LNPs for sustained expression, frozen-storage stability and potent vaccine immunotherapy

by Hui, A., Cai, R., Zhang, L., Huang, Z., Gu, H., Zheng, N., Chen, C.
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Created 27 Sep 2026

MYC-Hyperactivated Osteosarcoma Models Exhibit Resistance to Cabozantinib plus TIGIT Blockade

by Kappa, S. S., Patel, T., Nirala, B., Kurenbekova, L., Shuck, R., Yustein, J. T.
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Created 12 Sep 2026

Massively parallel characterization reveals context-dependent and non-additive regulatory effects of closely spaced variant pairs

by Kreevan, R., Pankratov, V., Yermakovich, D., Shukla, N., Metspalu, M., Eriksson, A., Dannemann, M., Gallego Romero, I., Org, T.
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