Preprints

Created 08 Oct 2026

Machine learning-assisted directed evolution yields dramatic improvement on novel AAV engineering task

by Luchner, M. R., Vorobieva, I., Makkar, R., Jozinovic, M., Chester, S., Wood, M. J. A., Sanders, S. J., Gupta, D., Steel, H.

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Created 15 Sep 2026

Closed, Automated CAR-T Cell Manufacturing: from Research to Point of Care production.

by Boudousquie, C., Migliorini, D., Esensten, J., Irving, M., Maillard, J., Vuillefroy de Silly, R., Pierson, Y., Widmer, V., Pedard, M., Morbidelli, M., Vannini, N., Nallet, E., Bellosta, L., Dutoit, L., Jammes, F.

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Created 23 Sep 2026

Dual-targeted nanoparticles enable the ex vivo generation of cytotoxic and phagocytic CAR effector cells

by Hong, J., Lim, J., Park, M., Song, J., Lee, B. J., Park, M., Shin, M.-K., Seo, H., Kang, H. J., Kim, B.-S., Lee, C.-H.

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Created 22 Sep 2026

Diversity of penicillin-binding protein 2x in Streptococcus pyogenes from England and Wales, 2001 to 2015

by Sveikauskaite, G., Marshall, A. L., Gorshkova, S., Guy, R. L., Wan, Y., Vieira, A., Coelho, J., Moganeradj, K., Sriskandan, S., Jauneikaite, E., Soo, V. W.

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Created 14 Sep 2026

Matched full-UDG and non-UDG ancient DNA libraries reveal trade-offs in post-mortem damage correction for imputation and kinship inference

by Ravdandorj, O., Sampildondov, C., Janchiv, K., Gakuhari, T.

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Created 24 Sep 2026

Fatty acid synthesis restricts HIV-1 infection through regulation of the nuclear envelope in CD4+ T cells

by Acklin, J. A., Ye, M., Pontillo, E. A., Woros, M. E., Krupa, E. H., Walker, B. D., Ringel, A. E.

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Created 15 Sep 2026

Divergent amyloid trajectories distinguish normal aging from Alzheimer's disease progression

by Tong, M., Gao, T., Upadhyaya, Y., Nho, K., Fang, S., Saykin, A., Yan, J., for the Alzheimer's Disease Neuroimaging Initiative

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Created 26 Sep 2026

Wall stiffening is a primary contributor to motility loss in Crohn's disease: an electromechanical modeling study

by Anantha Krishnan, A., Abubaker, M., Holland, M. A.

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Created 15 Sep 2026

Transcranial Random Aperiodic Stimulation Improves Working Memory Precision

by van Engen, Q., Riddle, J., Voytek, B.

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Created 16 Sep 2026

Multi-omics reveals a monocyte-macrophage-fibroblast axis in post-COVID-19 fibroinflammatory lung remodelling

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