Preprints

Created 12 Sep 2026

Brain-resident myeloid cells promote rapid leukocyte adhesion in leptomeningeal vessels after anti-Aβ immunotherapy

by Algamal, M., Yokomizo, S., Ndambakuwa, W., Abdallah, S., Sanchez-Mico, M. V., Gillani, R., da Silva, P., Rajput, A., Palanivelu, L., Lee, Y., Walsh, K. R., Kumar, S., Kilic, K., El Khoury, J., Izzy, S., Kozberg, M. G., Bacskai, B. J.

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Created 27 Aug 2026

CD24 Acts as an Evolutionarily Conserved Innate Immune Checkpoint in Colorectal Cancer

by Machado, A. B., Rebelo de Almeida, C., Azevedo, C. M., Viana, N., Fernandes, D. R., Povoa, V., Marques, F., Zilhäo, R., Ereno-Orbea, J., Jimenez-Barbero, J., Carlos, A. R., Pinho, S. S., Fior, R.

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Created 05 Sep 2026

NGS-RFA/FRA: A High Throughput Experimental and Computational Pipeline for Selective Mutational Scanning in Parallel

by Tureli, S., Bestebroer, T., James, S., Scheuer, R., Dahn, R., Fan, S., Turner, S., Wilks, S., Netzl, A., Hopping, A. M., Jones, T. C., Neumann, G., Kawaoka, Y., Fouchier, R. A. M., Richard, M., Smith, D. J.

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Created 31 Aug 2026

FlexiTAC enables controllable PROTAC linker generation across diverse structural settings using a Bayesian flow network with posterior guidance

by Li, Y., Zhao, Y., Zhou, L., Huang, C., Xu, Q., Chen, Y., Qin, Z., Fan, K., Yang, J., Cao, D.

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Created 14 Sep 2026

The Separable Organization of Immune Transcriptional Responses

by Zahid, H. J.

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Created 15 Sep 2026

Cell type-specific histone acetylation landscape in Alzheimer's disease reveals a putative role of MITF in microglia

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Created 27 Aug 2026

Tree-aware conditional language modeling recovers mutational patterns of viral evolution

by Polunina, P. V., Maier, W., Rubin, A. F.

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Created 26 Aug 2026

Brain-Resident CD8+ T Cells Regulate Neuronal Activity and Behavior via Interferon-Gamma

by park, k., jang, j., jeon, s., hwang, s., choi, k., cox, t., Ngiow, S., flores, j., harrison, c., liu, s., Bennett, F. C., silverman, m., Wherry, E. J., thaiss, c., fuccillo, m., Yim, Y. S.

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Created 27 Aug 2026

TEDDY: An integrative workflow for TE-chimeric isoform reconstruction and systematic characterization of TE-dependent transcriptional regulation

by Xiao, Y., Shen, L., Jiang, C., Zhang, Y., Liang, Y., Yin, J., Wang, H., Gao, S., Le, R., Shi, J.

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Created 06 Sep 2026

DNA aptamers to interfere with HasA, the hemophore of the heme assimilation system in Pseudomonas aeruginosa, as a potential antimicrobial strategy

by Bosetto, F., Wei, T., Stott, K., McLaughlin, S. H., Zacharopoulou, M., Itzhaki, L. S., Mela, I.

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