Preprints

Created 19 Sep 2026

Neoantigen-reactive CD8+ T cell engagement marks exceptional survivors of pancreatic cancer

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Created 13 Sep 2026

Interaction Profiles as a Universal Language for Generative Molecular Design with ShEPhERD-2

by Abeywardane, K. A., Walker, K., Coley, C. W.

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Created 15 Sep 2026

Cell type-specific histone acetylation landscape in Alzheimer's disease reveals a putative role of MITF in microglia

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Created 11 Sep 2026

Specificity-driven protein binder design with Odin-Multi

by Brasas, V., Christensen, C. R., Björnsson, K. H., Moller, V. E., Scapolo, B., Benard-Valle, M., Nygaard, M. M., Nielsen, J. C., Hadrup, S. R., Johansen, K. H., Jenkins, T. P.

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Created 08 Sep 2026

Inverse FoldDir: Structure-conditioned Protein Sequence Design by Dirichlet Flow Matching

by TARTICI, A., Stojkovic, M., Tian, A., Jewett, M. C., Altman, R. B., Wittmann, B. J.

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Created 02 Oct 2026

Veillonella dispar triggers dual-hits in the pathogenesis of autoimmune hepatitis and primary biliary cholangitis via testosterone depletion-BAFF-B cell axis and Th17 cell activation

by Liu, Y.-L., Xing, Q.-Q., Lin, X., Zeng, W.-W., Chen, Y.-H., You, Y.-Y., Zhou, L.-N., Chen, X.-N., Wu, M.-X., Xue, H.-X., Weng, S., Pan, J.-S.

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Created 18 Sep 2026

Integrating structural and biological evidence to rerank ESMFold2 protein-protein interactions

by Xie, J., Li, M., Chai, Y., Ou, G., Li, W., Guo, Z.

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Created 23 Sep 2026

Peripheral NaV1.7 modulation reveals divergent peripheral and central adaptations in persistent trigeminal pain

by Allen, H. N., Grabus, N. K., Khanna, R.

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Created 09 Sep 2026

End-to-end plaque counting and virus titration from laboratory plate images with deep learning

by Moris, E., Costable, A., Rey, S., Ferreiro, I., Hurtado, J., Villagran, M., Luciano, L. L., Vazquez, A. E., Ramos, J., Monteiro, I., de Santiago, M. V., Moreno, P., Moratorio, G., Orlando, J. I.

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Created 21 Sep 2026

A self-limiting, TREM2-dependent anabolic program confers microglial resilience in Alzheimer's disease

by Lin, D., Atkinson, J. R., Wu, W., Chen, M., Jayasekara, S., Segal, B. M., Ma, A., Gao, J.

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