Preprints

Created 23 Sep 2026

Peripheral NaV1.7 modulation reveals divergent peripheral and central adaptations in persistent trigeminal pain

by Allen, H. N., Grabus, N. K., Khanna, R.

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Created 08 Sep 2026

Reversible, Sexually Dimorphic Sympathetic Aging: Distal Axon Withdrawal Shaped by Prepubertal Gonadal Influences

by Pangilinan, G. R., Patil, S., Mires, F., Ye, G., Bogomilova, V., Tilley, L., Goldkorn, T., McGill, C. J., Ballou, N., Li, X., Jadhav, U., Benayoun, B. A., Shwartz, Y.

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Created 08 Sep 2026

Learning from tandem mass spectra at scale with a self-supervised foundation model for proteomics

by Nieuwoudt, M., Reverenna, M., Patel, D., Catzel, R., Houngue, I. H. J., Daniel, J., Eloff, K., Santos, A., Lopez Carranza, N., Jenkins, T. P., Van Goey, J., Kalogeropoulos, K.

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Created 11 Sep 2026

AutoScreen: AI Co-Scientist System for Target Discovery in Functional Genomics

by Qu, Y., Liu, X., Wang, X., Chen, M., Luo, X., Lyu, L., Yin, M., Hui, J., Yin, D., Dinesh, R., Qiu, L., Huang, K., Wang, H., Tong, S., Cousins, H., Feng, R., Martinez, O., Zhang, J., Chen, T., Altman, R., Leskovec, J., Regev, A., Wang, M., Cong, L.

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Created 27 Sep 2026

Pop-Corn: Predicting Perturbation Phenotype Effects Across Single-Cell and Spatial Contexts

by Chen, J., Cui, Y., Shao, Y., Sun, N., Martinez, M. R.

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Created 12 Sep 2026

Large-Vessel Venous Signal Confounds Apparent Amygdala Activation in BOLD fMRI

by Diamandis, Z., Tyszka, J. M., Adolphs, R.

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Created 16 Sep 2026

Multistate Enzyme Design Enables Efficient and Stereoselective Multistep Catalysis

by Pham, N. T. H., Guo, R., Garcia Jimenez, R. P., Hutton, A. E., Johannissen, L. O., Wehrstedt, J. A., Seifinoferest, B., Birch-Price, Z., Berreur, J., Hay, S., Thompson, M. C., Green, A. P., Chica, R. A.

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Created 14 Sep 2026

Lipid nanoparticle induced model endosomal membrane disruption

by Pramanik, S., Vasudevan, A., Liang, Z., Karole, A., Berchel, M., Jaffres, P.-A., Eygeris, Y., Sahay, G.

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Created 15 Sep 2026

Oxidized phosphatidylinositol impairs lysosomal membrane repair to promote ferroptosis

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Created 27 Sep 2026

Integrative analysis of the MDM2 promoter switch and cellular lineage plasticity in colorectal cancer: a contrast between the autonomous-proliferation type (CIN/CMS2) and the environment-adaptive type (MSI/gastric metaplasia)

by Tsukui, T., Tsuda, K., Yao, R., Shin, K.

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