Preprints

Created 18 Sep 2026

Cryo-EM Structures of Infectious Low-Twist α-Synuclein Filaments in Lewy Bodies

by Yan, N. L., Mayer, M., Melo, A. A., Ayers, J. I., Mordes, D. A., Seeley, W. W., Prusiner, S. B., Tse, E., Chittoor-Vinod, V. G., Merz, G. E.

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Created 15 Sep 2026

PAIR-Scan: Single-step identification of highly potent TCR-neoantigen pairs through library-on-library screening

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Created 14 Sep 2026

Nanoscale chemical tomography reveals organic and inorganic clusters in fossilised dinosaur tooth

by Hsu, Y., Schwarz, T., Triccas, A., Kostka, A., Chen, X., Jang, K., Scheu, C., Razker, B., Tuetken, T., Gault, B., Dumont, M.

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Created 18 Sep 2026

Generative Design of New-to-nature Biosynthetic Assembly Lines with Genomic Language Modeling

by Lanclos, N., Ibrahim, K., Cornman, A., Huang, M., Gill, V., Jiang, A., Abraham, J., Gin, J., Chen, Y., Petzold, C., Baerwald, J., Kortemme, T., Keasling, J., Hwang, Y.

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Created 17 Sep 2026

Incomplete references leave bulk deconvolution targets non-identifiable, but identification has a computable precision price

by Jiang, H., Gao, F., Liu, P., Wu, Y., Jie, Y., Li, Y., Jiang, Y.

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Created 17 Sep 2026

First evidence for TIGR-Tas activity in a photosynthetic eukaryote

by Jaeyeon, L., Kyeongjun, K., Hyeonmin, R., Hyeonsik, Y., Kerstin, D., Mid-Eum, P., Joong-Tak, Y., Bon-Kyoung, K., Ji-Hye, Y., Ho-Seok, L., Eun Yu, K.

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Created 15 Sep 2026

H3K27me3 Drives Constricted Migration Induced 3D Genome Rewiring in Melanoma

by Olajide, T. H., Ajagbe, M. A., Rodriguez Gonzalez, A., Ijadunola, H., Ross, C., Eisenklam, L., Swets, A., McCord, R. P.

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Created 18 Sep 2026

Programmable DNA Assemblies Reconstitute Supramolecular Protein Function

by Gandavadi, D., Dwivedy, A., Manoharaan, R., Im, S., Umrao, S., Hoang, C., Hammoud, K., Nguyen, L., Zhao, Y., Bhargava, R., Wang, X.

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Created 11 Sep 2026

Painting the evolutionary history of a multicompartmentalized syngameon in North American Castilleja (Orobanchaceae)

by Santos, M. A., Jacobs, S. J., Latvis, M., Harrington, S., Tank, D. C.

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Created 09 Sep 2026

Variant-specific nucleocapsid mutations shape host innate immune trajectories during SARS-CoV-2 infection

by Berger, J. M., Schroeder, J. M., Soh, T. K., Pekarek, N., Breul, L.-M., Doerner, S., Bluemke, P., Huang, J., Bosse, J. B., Pfefferle, S., Uetrecht, C.

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