Preprints

Created 19 Aug 2026

Chromosomal instability shapes spatial and temporal phenotypic diversity in a malignant peripheral nerve sheath tumour

by Yan, H., Demeulemeester, J., Verfaillie, A., Cheng, Y., Pan, Y., Cotobal Martin, C., Ward, S., Stein, A., Lesluyes, T., Kaufmann, T., Schwarz, R. F., Voet, T., Swanton, C., Zaccaria, S., Flanagan, A. M., Tarabichi, M., Van Loo, P.

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Created 20 Aug 2026

A Persistent Fleet of AI Scientists Exhibits Cooperative and Autopoietic Behavior

by Patel, M. S., Wierson, W. A., Ekker, S. C.

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Created 20 Aug 2026

Signature Recontextualization: Mapping perturbational signatures across biological contexts

by Chen, A. D., Girke, T., Monti, S.

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Created 20 Aug 2026

When adiposity and listening to reasons for behavioral change make food choices healthier: Behavioral and neural mediators of weight status effects on dietary decision-making following behavioral change interventions.

by Flament, B., Rodrigues, B., Khalid, I., Rotge, J. Y., Poitou-Bernert, C., Plassmann, H., Schmidt, L.

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Created 26 Aug 2026

Connectome-constrained modeling identifies neurons and synapses that sustain spontaneous activity in Drosophila

by Li, Q., Ping, W., Zhang, K., Wang, C.

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Created 19 Aug 2026

A Generative Virtual Tissue Model Enables Computational Design of Therapeutic Perturbation Strategies

by Lu, Y., Zhang, W., Chen, Y.-J., Yin, J., Chen, L., Fleisher, K., Gornet, J., Liu, R., Wang, Z. J., Poon, Y., You, Y., Thomson, M.

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Created 19 Aug 2026

Spatial microRNA profiling at single-cell resolution by in situ barcoded extension

by Robles-Remacho, A., Zou, Y., Jensen, A., Tricopoulos, C., Grillo, M., Nilsson, M.

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Created 04 Sep 2026

Microbial valerate is associated with CAR T dysbiosis and its supplementation enhances CAR T function in B-cell lymphoma

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Created 13 Sep 2026

Inhibitors of HIV-1 maturation modulate conformational dynamics and heterogeneity of the immature Gag lattice

by Nandi, T., Wong, M., Waheed, A. A., Freed, E. O., Schiffer, C. A., Munro, J. B.

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Created 16 Aug 2026

De novo design of autocatalytically forming intra- and intermolecular isopeptide bonds to construct rigid covalent protein assemblies

by Milles, L. F., Huddy, E. B., Carr, A., Hsia, Y., Li, X., Kang, A., Sankaran, B., Bera, A. K., Baker, D.

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