Preprints

Created 16 Sep 2026

A single cortical circuit implements fast and slow visual search

by Pagnotta, M. F., Zhuang, H., Slama, S. J. K., King-Stephens, D., Laxer, K. D., Endestad, T., Solbakk, A.-K., Lin, J. J., Knight, R. T.

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Created 10 Sep 2026

Proteoform plasticity modulates the temperature response in circadian timekeeping

by Pelham, J. F., Keeley, A. T., Usher, E. T., Martinsen, J. H., Jankowski, M. S., Moses, D., Mosier, A. E., Thomas, J., Buckley, N. D., Kragelund, B. B., Sukenik, S., Holehouse, A. S., Hurley, J. M.

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Created 20 Sep 2026

Identifying Putative Pathogenic Non-Coding Variants in Unresolved Rare Disease Patients Using Topologically Associated Domains

by Gacita, A. M., Pahl, M., Torres, M. D., Ganesan, S., Blair, J. J., Patel, K., Ramakrishnan, R., Conlin, L., Helbig, I., Grant, S. F. A.

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Created 15 Sep 2026

Cross-platform multi-laboratory screening identifies HUWE1, USP33 and USP20 as negative-regulators of autophagy or mitophagy with relevance to neurodegeneration

by Giudici, M. L., Coode, E., Au, W. H., Rey, C., Manifava, M., Capatina, O.-G., Aldred, G., Milde, S., Zyka, V., Kuan, W.-L., Duce, J., Clarke, J. H., Whitworth, A. J., Ktistakis, N. T., Skidmore, J.

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Created 03 Oct 2026

ALS/FTD-linked TDP-43 alterations prevent HSV-1 infection by disrupting cell-adhesion pathways

by Jackvony Infurna, S., Ijaz, L., Hardin, E. J., Aikedan, A., Zhou, C., Yadavalli, T., Jang, M. W., Mahoney, M., Gan, L., Shukla, D., Orr, A. L., Orr, A. G.

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Created 10 Sep 2026

Cell Painting-Based Tool for the Risk Assessment of Mammary Carcinogens and Endocrine Disruptors

by ACHEBOUCHE, R., Taboureau, O.

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Created 29 Sep 2026

Unified modeling of mutation-induced protein stability responses with OmegaTherm

by Wang, W., Zhou, Y., Yu, W., Wu, Y., Yang, Q., Zheng, R., Huang, X., Li, M., Zhang, Y.

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Created 12 Sep 2026

Causal variant underestimation is a major overlooked driver of sequence-to-function model underperformance

by Drusinsky, S., Pollard, K. S.

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Created 19 Sep 2026

Genome-wide characterization of host factors involved in single-stranded RNA and DNA phage infection pathways

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Created 14 Sep 2026

Importance of the Unseen: Near-Infrared Light Regulates Human Glucose Levels in the Built Environment

by Meihami, K., Unwin Teji, J., Barrett, E., Jeffery, G.

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